Paper Details 
Original Abstract of the Article :
Diabetes is a global epidemic that poses a severe challenge to public health. The characteristic features of this disease are hyperglycemia and deterioration of the function of pancreatic β-cells, which leads to oxidative stress and organ damage. Glimepiride is used to treat type II diabetes bu...See full text at original site
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引用元:
https://doi.org/10.1039/d2bm00344a

データ提供:米国国立医学図書館(NLM)

Peptide Gels: A Promising Approach for Diabetes Treatment

The field of drug delivery is constantly seeking innovative ways to improve the effectiveness and safety of medications. This research explores the potential of self-assembled peptide gels for the controlled release of glimepiride, a commonly used antidiabetic drug. The study investigates the use of di- and tripeptides with inherent antioxidant properties to create biocompatible gels capable of sustained drug release and pH-responsive delivery. These findings pave the way for a novel approach to diabetes management.

Peptide Gels: A Multifaceted Solution

The study's findings demonstrate the potential of self-assembled peptide gels to overcome the challenges associated with glimepiride treatment, including its short half-life and potential for hypoglycemia. These gels exhibit excellent viscoelastic properties, self-healing abilities, and antioxidant activity. The research also highlights the pH-responsive nature of these gels, allowing for controlled drug release based on the environment. This innovative approach offers a promising alternative to conventional drug delivery methods.

A Novel Approach to Diabetes Care

This research offers a glimpse into the future of diabetes management. The development of peptide gels for controlled drug delivery has the potential to significantly improve the lives of individuals with diabetes by reducing the risks of hypoglycemia and improving overall glycemic control. This research is a testament to the creativity and innovation driving the field of drug delivery.

Dr. Camel's Conclusion

This research is a camel caravan carrying a treasure trove of potential solutions for diabetes management. These peptide gels are like a hidden oasis in the vast desert of drug delivery, offering a refreshing and effective approach to treating this complex disease.

Date :
  1. Date Completed 2022-05-05
  2. Date Revised 2022-05-05
Further Info :

Pubmed ID

35356961

DOI: Digital Object Identifier

10.1039/d2bm00344a

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SNS
PICO Info
in preparation
Languages

English

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