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Effects of aspirin on dementia and cognitive function in diabetic patients: the ASCEND trial.

Author: ArmitageJane, BartonJill, BowmanLouise, BuckGeorgina, CollinsRory, HaynesRichard, MafhamMarion, OfferAlison, ParishSarah, StevensWilliam, WallendszusKarl

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

The ASCEND trial, which involved 15,480 people with diabetes, found no large proportional effect of aspirin on the risk of dementia.
Paper Details　
Original Abstract of the Article :
AIMS: Aspirin is widely used in cardiovascular disease prevention but is also associated with an increased risk of bleeding. The net effect of aspirin on dementia and cognitive impairment is uncertain. METHODS AND RESULTS: In the ASCEND trial, 15 480 people from the UK with diabetes and no history ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242621/

データ提供：米国国立医学図書館（NLM）

Aspirin and Dementia in Diabetic Patients: The ASCEND Trial

This study takes us on a journey through the vast desert of [cardiovascular disease] and its impact on [dementia]. It's like exploring a desert with hidden oases, seeking to understand the complex relationship between [aspirin] and [cognitive function] in diabetic patients. The researchers conducted a [randomized trial] with over 15,000 participants to evaluate the long-term effects of [aspirin] on [dementia and cognitive impairment]. The study revealed that [aspirin] did not have a significant impact on the risk of [dementia] in patients with diabetes.

Aspirin's Impact on Dementia in Diabetic Patients

The results of this study challenge the common perception of [aspirin] as a potential protective factor against [dementia] in diabetic patients. They found that [specify the main findings]. This information can help guide clinical decisions regarding the use of [aspirin] in this population.

Navigating the Desert of Cognitive Health

This study sheds light on the complex relationship between [aspirin] and [cognitive health] in diabetic patients. It's like discovering a new pathway through the desert, revealing that [aspirin] may not be the key to preventing [dementia]. The researchers provide valuable insights into the potential benefits and risks associated with the use of [aspirin] in this population, helping us navigate the desert of cognitive health.

Dr.Camel's Conclusion

This large-scale randomized trial, ASCEND, provides valuable insights into the relationship between [aspirin] and [dementia] in diabetic patients. While the study found no significant effect of [aspirin] on the risk of [dementia], it highlights the importance of ongoing research to better understand the complex interplay between [aspirin], [diabetes], and [cognitive health]. The results of this study can help guide clinical decisions regarding the use of [aspirin] in diabetic patients and contribute to the development of effective strategies for preventing and managing cognitive decline.
Date :
  1. Date Completed 2022-06-02
  2. Date Revised 2023-02-15
Further Info :

Pubmed ID

35393614

DOI: Digital Object Identifier

PMC9242621

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Article Analysis
・Effects of aspirin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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