A multiple-dose comparison of ketorolac tromethamine with diflunisal and placebo in postmeniscectomy pain.

Author: HonigW J, Van OchtenJ

Paper Details 
Original Abstract of the Article :
The efficacy of oral ketorolac 5 mg and 10 mg taken qid was compared in a randomized double-blind study with that of oral diflunisal 500 mg bid (interleaved with placebo twice daily) and of placebo, in 120 patients suffering at least moderate pain following meniscectomy. The trial comprised two phas...See full text at original site
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引用元:
https://doi.org/10.1002/j.1552-4604.1986.tb02976.x

データ提供:米国国立医学図書館(NLM)

Ketorolac Tromethamine: A Powerful Pain Reliever for Post-Meniscectomy Pain

Post-meniscectomy pain is a common challenge for patients undergoing knee surgery. The research team aimed to evaluate the efficacy of oral ketorolac in managing this pain, comparing it to diflunisal and placebo. The study design involved a randomized, double-blind trial with 120 participants who experienced moderate to severe pain after meniscectomy. The researchers assessed pain levels during both an acute phase (the first postoperative day) and a chronic phase (days 2-5 postoperatively), using visual analogue scales. The results indicate that ketorolac, at both 5 mg and 10 mg doses, demonstrated a significant improvement in pain relief compared to placebo, especially during the chronic phase.

Ketorolac: A Suitable Option for Post-Operative Pain Management

Ketorolac 10 mg provided the most pain relief during the chronic phase, while ketorolac 5 mg and placebo showed similar effects. Diflunisal, on the other hand, showed the least pain relief. Interestingly, all active treatments demonstrated a low incidence of side effects, suggesting a favorable safety profile. In conclusion, the study suggests that ketorolac could be a suitable therapeutic option for managing acute postoperative pain following meniscectomy, particularly during the chronic phase.

Ketorolac: Navigating Pain Relief in the Desert of Post-Surgery Recovery

Like the desert, post-meniscectomy recovery can be a challenging landscape for patients. However, this research suggests that ketorolac, a potent pain reliever, can be a valuable oasis in the recovery process. By effectively managing pain, it can help individuals navigate this journey with greater comfort and potentially contribute to a smoother and quicker return to daily activities. As a reminder, it's always essential to consult with your physician before taking any medication, especially after surgery. They can provide personalized guidance based on your individual needs and medical history.

Dr.Camel's Conclusion

Ketorolac is a promising option for managing post-meniscectomy pain, especially in the chronic phase. This drug effectively reduces pain without causing significant side effects. Think of ketorolac as a cool, refreshing spring in the desert of pain, offering relief and a smoother journey towards recovery.

Date :
  1. Date Completed 1987-02-04
  2. Date Revised 2019-08-24
Further Info :

Pubmed ID

3540032

DOI: Digital Object Identifier

10.1002/j.1552-4604.1986.tb02976.x

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SNS
PICO Info
in preparation
Languages

English

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