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Non-steroidal anti-inflammatory drugs (NSAIDs), pain and aging: Adjusting prescription to patient features.

Author: AndradeJosé Paulo, DouradoMarília, LiraLuís, MarquesDenise, NapoleãoLeonardo, RibeiroHugo, RodriguesInês, VeríssimoManuel

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This narrative review discusses the pharmacokinetics of NSAIDs and their implications for patient safety. The authors highlight the benefits of lower renal excretion and phase 2 metabolism for patients requiring frequent NSAID use, particularly elderly patients and those with cardiovascular disease or impaired renal function.
Paper Details　
Original Abstract of the Article :
A narrative review of papers published from January 2011 to December 2021, after a literature search in selected databases using the terms "pharmacokinetics", "ibuprofen", "diclofenac", "acemetacin", "naproxen", "etodolac" and "etoricoxib" was performed. From 828 articles identified, only eight met ...See full text at original site
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引用元：
https://doi.org/10.1016/j.biopha.2022.112958

データ提供：米国国立医学図書館（NLM）

A Balancing Act: Navigating NSAID Prescription for Aging Patients

The use of [non-steroidal anti-inflammatory drugs (NSAIDs)] for managing pain is widespread, but careful consideration is needed, especially for [aging patients]. This research explores the complex landscape of NSAID prescription, considering individual patient characteristics and the potential for adverse effects. Think of NSAIDs as a powerful desert wind, capable of both providing relief and carrying with it the risk of sandstorms. This research guides healthcare professionals in safely navigating this terrain.

A Personalized Approach to Pain Management

The study highlights the importance of tailoring NSAID prescription to individual patient needs, comparing it to choosing the right tools for a specific desert expedition. Factors such as age, pre-existing conditions, and concurrent medications are carefully considered to minimize the risk of adverse effects. This research emphasizes the need for a personalized approach, considering the unique landscape of each patient's health.

A Sensible Approach to NSAID Use

This research provides valuable insights for healthcare professionals in managing pain in aging patients. By understanding the pharmacokinetic properties and potential risks associated with different NSAIDs, healthcare professionals can prescribe these medications more safely and effectively, ensuring the well-being of their patients. It's a reminder that a thoughtful approach to pain management is essential for promoting overall health.

Dr.Camel's Conclusion

This research is like a compass, guiding healthcare professionals through the intricate terrain of NSAID prescription for aging patients. By considering the individual characteristics of each patient, healthcare providers can choose the most appropriate NSAID, ensuring safe and effective pain management. This research is a testament to the importance of a personalized approach to patient care.

Date :
  1. Date Completed 2022-06-03
  2. Date Revised 2022-06-03
Further Info :

Pubmed ID

35453005

DOI: Digital Object Identifier

10.1016/j.biopha.2022.112958

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Languages

English

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