Does previous use of tumour necrosis inhibitors change the therapeutic effect of interleukin (IL)-17 or IL-12/23 inhibitors on psoriasis and psoriatic arthritis? Results of a systematic review.

Author: LiuYang, XieYan

Paper Details 
Original Abstract of the Article :
BACKGROUND: Tumour necrosis factor inhibitors (TNFi) were the first biologics approved for the treatment of psoriasis (PsO) and psoriatic arthritis (PsA). However, some patients are intolerant of or unresponsive to TNFi. AIM: To investigate the therapeutic effect of interleukin (IL)-17 and IL-12/23...See full text at original site
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引用元:
https://doi.org/10.1111/ced.15237

データ提供:米国国立医学図書館(NLM)

TNF-alpha Inhibitors: A New Path for Psoriasis Treatment

Psoriasis is a chronic inflammatory skin condition that can significantly impact a person's life. This research explores the therapeutic effects of interleukin (IL)-17 and IL-12/23 inhibitors in patients with psoriasis or psoriatic arthritis who have not responded well to traditional TNF-alpha inhibitors. It's like exploring a new oasis, hoping to find a more effective treatment for this challenging condition.

The researchers conducted [research methods] to assess the effectiveness of IL-17 and IL-12/23 inhibitors in patients with psoriasis or psoriatic arthritis who had previously failed to respond to TNF-alpha inhibitors. Their findings indicate that IL-17 inhibitors show promise for these patients, offering a potential alternative treatment path.

A New Oasis in the Desert of Psoriasis

This study suggests that IL-17 inhibitors, like a newly discovered oasis, offer a potential solution for patients with psoriasis or psoriatic arthritis who have not responded well to traditional TNF-alpha inhibitors. This discovery provides hope for a better future for these individuals.

Finding Relief in the Sandstorm of Psoriasis

This study underscores the importance of finding the right treatment for psoriasis. It's like finding a safe haven in the midst of a sandstorm. By exploring different treatment options, like IL-17 inhibitors, we can provide patients with a better chance at managing their condition and finding relief.

Dr.Camel's Conclusion

The study provides valuable insights into the potential of IL-17 inhibitors for treating patients with psoriasis or psoriatic arthritis who have not responded well to TNF-alpha inhibitors. It highlights the importance of exploring new avenues in treatment, like discovering a hidden oasis in the vast desert of medicine.

Date :
  1. Date Completed 2022-08-22
  2. Date Revised 2022-08-24
Further Info :

Pubmed ID

35466472

DOI: Digital Object Identifier

10.1111/ced.15237

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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