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Bipolar disorder treatment according to illness trajectory: a systematic review of clinical trials.

Author: Antonelli-SalgadoThyago, ErthalIsadora Nunes, LopesSávio Luiz Santos, LucasLuiza Silveira, MarchionattiLauro Estivalete, PassosIves Cavalcante, RebouçasDiego Barreto

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Current bipolar disorder treatment focuses on preventing episodes and managing them during acute phases, but less attention is given to how the illness progresses over time. This review examined studies that investigated the impact of illness progression on treatment effectiveness. While studies found that treatment effectiveness decreases as the illness progresses, supporting the idea of early intervention, there wasn't enough information to recommend specific treatments based on different stages of the illness. The review also identified areas where future research could be improved, suggesting the use of a standardized system to categorize the stage of the illness.
Paper Details　
Original Abstract of the Article :
The current bipolar disorder treatment guidelines focus mainly on the prevention of recurrence and stabilization of acute mood episodes while neglecting outcomes related to the longitudinal course of illness. We systematically reviewed studies that assess the impact of disease progression in the tre...See full text at original site
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引用元：
https://doi.org/10.1016/j.psychres.2022.114572

データ提供：米国国立医学図書館（NLM）

Tailoring Bipolar Disorder Treatment: A Journey Through the Illness Trajectory

This systematic review examines the impact of illness trajectory on treatment outcomes in bipolar disorder. The authors critically analyzed clinical trials that assessed the effects of treatment across different stages of illness progression, including number of prior episodes, disease length, and clinical staging models. Their findings highlight the importance of tailoring treatment strategies to individual patient characteristics, specifically considering the stage of illness progression to optimize outcomes and improve long-term management.

Navigating the Shifting Sands of Bipolar Disorder

This research, like a caravan navigating the ever-changing landscape of bipolar disorder, explores the complexities of treatment across different stages of illness progression. The authors critically analyzed data from multiple studies, revealing the importance of considering the individual patient's illness trajectory when tailoring treatment strategies. The findings underscore the need for more personalized approaches that acknowledge the dynamic nature of this complex condition.

A Compass for Personalized Bipolar Disorder Care

This study, like a compass guiding us through the intricate pathways of bipolar disorder, highlights the importance of individualizing treatment strategies based on the patient's stage of illness progression. The findings suggest that earlier intervention and tailored treatments may lead to improved long-term outcomes for patients. However, the authors emphasize the need for further research to establish more definitive recommendations for treatment across different stages of illness.

Dr.Camel's Conclusion

This research, like a desert explorer mapping the shifting sands of bipolar disorder, highlights the importance of considering individual patient factors, particularly the stage of illness progression, when developing treatment strategies. The study underscores the need for a more personalized approach to managing this complex condition, aiming to optimize outcomes and improve the long-term well-being of patients.

Date :
  1. Date Completed 2022-05-19
  2. Date Revised 2022-06-10
Further Info :

Pubmed ID

35490572

DOI: Digital Object Identifier

10.1016/j.psychres.2022.114572

Related Literature

Article Analysis
・Effective treatment of bipolar disorder
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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