Active Pharmacovigilance Project on the safety profile of Dolutegravir in Brazil.

Author: CeccatoMaria das Graças Braga, CostaAndré Moura Gomes da, Crepalde-RibeiroKennedy, Furtado Dos SantosSimone, MendesJullye Campos, PantuzzaLais Lessa Neiva, ReisAdriano Max Moreira, SilveiraMicheline Rosa

Paper Details 
Original Abstract of the Article :
A quantitative descriptive study based on Brazilian Active Pharmacovigilance of Dolutegravir (DTG) Project was performed to describe the adverse drug reactions (ADRs) to DTG reported and to evaluate the noncompleteness of data from DTG active pharmacovigilance in Brazil. ADRs and clinical and indivi...See full text at original site
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引用元:
https://doi.org/10.1080/09540121.2022.2062289

データ提供:米国国立医学図書館(NLM)

Active Pharmacovigilance of Dolutegravir in Brazil: Assessing Safety and Tolerability

This quantitative descriptive study delves into the safety profile of dolutegravir (DTG), a medication used to treat HIV infection. The authors analyzed data from Brazil's active pharmacovigilance program for DTG, focusing on adverse drug reactions (ADRs) reported from April 2017 to August 2019. The study provides valuable insights into the safety and tolerability of DTG in a real-world setting, contributing to the ongoing evaluation of this important medication.

Evaluating the Safety Profile of Dolutegravir

The authors conducted a comprehensive analysis of ADRs reported during the active pharmacovigilance of DTG in Brazil, providing a real-world perspective on the medication's safety profile. Their findings suggest that DTG has a relatively low frequency of ADRs, indicating good tolerability and safety. The study also highlights the importance of ongoing pharmacovigilance programs in monitoring the long-term safety of medications.

Implications for HIV Management: Ensuring Patient Safety and Optimizing Treatment

This study provides valuable information for clinicians managing HIV patients. The findings suggest that DTG is a well-tolerated and safe medication, offering a promising treatment option for individuals living with HIV. However, the authors emphasize the importance of remaining vigilant in monitoring patients for any potential ADRs. Just as a camel carefully navigates treacherous desert terrain, healthcare professionals must be attentive to potential risks and adjust treatment plans as needed to ensure patient safety and optimal outcomes.

Dr. Camel's Conclusion

This research provides valuable insights into the safety profile of Dolutegravir, highlighting its good tolerability and safety in a real-world setting. Active pharmacovigilance programs are crucial for ensuring the safe and effective use of medications, particularly in the long-term management of chronic conditions. As a researcher, I am encouraged by the ongoing efforts to monitor medication safety and optimize treatment strategies for patients living with HIV.

Date :
  1. Date Completed 2023-05-03
  2. Date Revised 2023-05-08
Further Info :

Pubmed ID

35578399

DOI: Digital Object Identifier

10.1080/09540121.2022.2062289

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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