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Benefits and drawbacks of statins and non-statin lipid lowering agents in carotid artery disease.

Author: AntignaniPier Luigi, ChaturvediSeemant, ComerotaAnthony J, DardikAlan, DaviesAlun H, EcksteinHans-Henning, FaggioliGianluca, Fernandes E FernandesJose, FraedrichGustav, GeroulakosGeorge, GloviczkiPeter, GolledgeJonathan, GuptaAjay, GurevichVictor S, JawienArkadiusz, JezovnikMateja K, KakkosStavros K, KnoflachMichael, LanzaGaetano, LiapisChristos D, LoftusIan M, MansilhaArmando, MikhailidisDimitri P, NicolaidesAndrew N, ParaskevasKosmas I, PiniRodolfo, PoredosPavel, ProczkaRobert M, RiccoJean-Baptiste, RundekTatjana, SabaLuca, SchlachetzkiFelix, SilvestriniMauro, SpinelliFrancesco, StiloFrancesco, SuriJasjit S, SvetlikovAlexei V, VeithFrank J, ZeebregtsClark J

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This multi-disciplinary overview recommends statins and PCSK9 inhibitors for patients with carotid stenosis, regardless of their LDL-C levels, as these medications significantly reduce stroke, cardiovascular mortality, and coronary event rates. The benefits outweigh the risks and potential side effects.
Paper Details　
Original Abstract of the Article :
International guidelines strongly recommend statins alone or in combination with other lipid-lowering agents to lower low-density lipoprotein cholesterol (LDL-C) levels for patients with asymptomatic/symptomatic carotid stenosis (AsxCS/SCS). Lowering LDL-C levels is associated with significant reduc...See full text at original site
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引用元：
https://doi.org/10.1016/j.pcad.2022.05.003

データ提供：米国国立医学図書館（NLM）

Statins and Non-Statin Lipid-Lowering Agents in Carotid Artery Disease: A Comprehensive Review

The field of cardiology is constantly seeking ways to prevent and treat cardiovascular disease. This study examines the role of lipid-lowering medications in managing carotid artery disease, a condition that affects the arteries in the neck. Researchers reviewed the benefits and risks of statins and non-statin lipid-lowering agents in patients with asymptomatic or symptomatic carotid stenosis. Their analysis provides valuable insights into the use of these medications for patients with carotid artery disease.

Lowering Cholesterol: A Key Strategy for Carotid Artery Disease

This research confirms the importance of lowering low-density lipoprotein cholesterol (LDL-C) levels in patients with carotid artery disease. Statins and PCSK9 inhibitors have been shown to be effective in reducing LDL-C levels and lowering the risk of stroke and other cardiovascular events.

Maintaining Cardiovascular Health: A Lifestyle Approach

In addition to medications, lifestyle modifications, such as a healthy diet, regular exercise, and smoking cessation, can significantly improve cardiovascular health.

Dr. Camel's Conclusion

This study is like a guidebook for navigating the complex world of lipid-lowering medications for carotid artery disease. The research underscores the importance of a multi-faceted approach, including medication and lifestyle modifications, to manage this condition.

Date :
  1. Date Completed 2022-09-13
  2. Date Revised 2022-09-20
Further Info :

Pubmed ID

35605696

DOI: Digital Object Identifier

10.1016/j.pcad.2022.05.003

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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