[A Pharmacist's Query Avoiding Exacerbation of Adverse Effects in a Patient with Acyclovir Encephalopathy: A Case Report].

Author: HouchiHitoshi, KosakaShinji, KurokawaNaohiro, MatsubaraAki, MotokiTakahiro, ShinmuraWataru, TaiTatsuya, TanakaHiroaki, WatanabeMasahiro, YamaguchiKazunori

Paper Details 
Original Abstract of the Article :
We report a haemodialysis patient with end-stage renal failure whom a pharmacist aided in the management of acyclovir (ACV) encephalopathy, which may have been related to valacyclovir hydrochloride (VACV) administered without sufficient dose reduction. The patient 78 years was admitted with a tentat...See full text at original site
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引用元:
https://doi.org/10.1248/yakushi.21-00237

データ提供:米国国立医学図書館(NLM)

A Pharmacist's Intervention: A Timely Oasis in the Desert of Acyclovir Encephalopathy

Acyclovir (ACV) encephalopathy, like a treacherous desert mirage, can pose a serious threat to patients with renal impairment. This case report highlights the critical role of a pharmacist in recognizing and managing this potentially life-threatening condition.

Pharmacist's Vigilance: A Beacon of Hope

The pharmacist's keen observation and timely intervention, like a desert oasis providing much-needed relief, led to the recognition of ACV encephalopathy in a patient who had received valacyclovir hydrochloride (VACV) without adequate dose reduction. The pharmacist, recognizing the potential for adverse effects, alerted the attending physician, leading to the discontinuation of ACV and initiation of continuous hemodiafiltration (CHDF) therapy.

Health Implications and Application

This case underscores the importance of close monitoring and careful dose adjustments for ACV in patients with renal impairment. Pharmacists, like vigilant guardians in the desert, play a crucial role in ensuring patient safety by identifying and addressing potential drug interactions and adverse effects. This case report serves as a reminder of the importance of pharmacovigilance and the essential contributions of pharmacists in patient care.

Dr.Camel's Conclusion

The desert of medication management is vast and complex, filled with potential pitfalls and hidden dangers. This case report reminds us that vigilance and timely intervention, like the oasis in the desert, can make a life-altering difference in patient care. Pharmacists, like skilled desert navigators, play a vital role in ensuring patient safety by recognizing and managing potential adverse effects. Their contributions are a testament to the importance of collaborative care and the power of expertise in navigating the complexities of medicine.

Date :
  1. Date Completed 2022-07-06
  2. Date Revised 2022-07-06
Further Info :

Pubmed ID

35781507

DOI: Digital Object Identifier

10.1248/yakushi.21-00237

SNS
PICO Info
in preparation
Languages

Japanese

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