Evaluation of four chemotherapy regimens for treatment of advanced AIDS-associated Kaposi sarcoma in Kenya: a cost-effectiveness analysis.

Author: BassettIngrid V, BusakhalaNaftali, ByakwagaHelen, FreedbergKenneth A, FreemanEsther E, Hajny FernandezMaya E, HyleEmily P, KipronoSamson, Laker-OkettaMiriam, MartinJeffery N, MaurerToby, McCannNicole C, PeiPamela P, ReddyKrishna P, SemeereAggrey

Paper Details 
Original Abstract of the Article :
The most effective treatment for advanced AIDS-associated Kaposi sarcoma is paclitaxel or pegylated liposomal doxorubicin (PLD); neither is routinely used in sub-Saharan Africa due to limited availability and high cost. We examined the clinical impact, costs, and cost-effectiveness of paclitaxel or ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/35839816

データ提供:米国国立医学図書館(NLM)

Cost-Effectiveness of Chemotherapy Regimens for Advanced AIDS-Associated Kaposi Sarcoma in Kenya

The field of [global health] is focused on finding cost-effective solutions for treating [AIDS-associated Kaposi sarcoma] (KS) in resource-limited settings. This study examines the cost-effectiveness of four different chemotherapy regimens for treating advanced KS in Kenya: [paclitaxel], [pegylated liposomal doxorubicin] (PLD), [etoposide], and [bleomycin-vincristine]. The study found that [paclitaxel] and [PLD] are the most effective treatments for advanced KS, but their high cost and limited availability in sub-Saharan Africa pose challenges. The study highlights the need for strategies to improve access to these effective treatments and to develop alternative approaches that are both effective and affordable.

Cost-Effectiveness Analysis: Balancing Efficacy and Affordability

This study demonstrates the importance of conducting cost-effectiveness analyses in evaluating treatment options, particularly in resource-limited settings. The findings highlight the need for a balance between efficacy and affordability when choosing treatments for KS. The study underscores the need for innovative approaches to improve access to effective and affordable treatments for KS in sub-Saharan Africa and to ensure that patients have access to the best possible care.

Improving Access to Effective Cancer Treatments in Resource-Limited Settings

This research underscores the challenges faced in providing effective cancer care in resource-limited settings. The study highlights the need for strategies to improve access to [paclitaxel] and [PLD], potentially through [drug donation programs], [cost-sharing mechanisms], or [local production initiatives]. The study also emphasizes the importance of developing [alternative treatments] that are both effective and affordable, addressing the critical need for equitable access to high-quality cancer care globally.

Dr. Camel's Conclusion

Just as a camel must navigate a harsh and unforgiving desert to find sustenance, healthcare providers in resource-limited settings face the challenge of providing effective care with limited resources. This study highlights the need for innovative solutions to ensure access to life-saving treatments for AIDS-associated Kaposi sarcoma, ensuring that everyone has a chance to thrive, no matter where they live.

Date :
  1. Date Completed 2022-07-19
  2. Date Revised 2023-08-31
Further Info :

Pubmed ID

35839816

DOI: Digital Object Identifier

NIHMS1808674

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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