Maternal and infant renal safety following tenofovir disoproxil fumarate exposure during pregnancy in a randomized control trial.

Author: , BaltrusaitisKristin, BrowningRenee, FairlieLee, FowlerMary Glenn, GeorgeKathleen, HeckmanBarbara, KnowlesKevin, MakananiBonus, MoodleyDhayendre, NyakudyaLynette H, SiberryGeorge K, Stranix-ChibandaLynda, TahaTaha E, TheronGerhard, TierneyCamlin, TomuMusunga

Paper Details 
Original Abstract of the Article :
Tenofovir disoproxil fumarate (TDF) in combination with other antiretroviral (ARV) drugs has been in clinical use for HIV treatment since its approval in 2001. Although the effectiveness of TDF in preventing perinatal HIV infection is well established, information about renal safety during pregnancy...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297643/

データ提供:米国国立医学図書館(NLM)

Tenofovir Disoproxil Fumarate During Pregnancy: Evaluating Renal Safety

Tenofovir disoproxil fumarate (TDF) is a cornerstone of HIV treatment, but its use during pregnancy has raised concerns about potential renal safety. This study, published in [journal name], aimed to assess the renal safety of TDF in pregnant women and their infants. The authors conducted a randomized controlled trial to compare the effects of TDF to other antiretroviral drugs.

While the study did not find any significant evidence of renal complications in either the mothers or their infants, the authors highlight the need for ongoing research and monitoring to further assess the long-term safety of TDF during pregnancy.

Navigating HIV Treatment During Pregnancy: A Balancing Act of Safety and Efficacy

This research highlights the importance of carefully considering the potential risks and benefits of different medications during pregnancy, especially when treating complex conditions like HIV. The study provides valuable data regarding the renal safety of TDF, but further research is needed to fully understand its long-term impact on both mothers and infants.

Understanding the Importance of Ongoing Research in Maternal and Infant Health

The study emphasizes the importance of ongoing research in evaluating the safety of medications during pregnancy. This type of research is crucial in ensuring the well-being of both mothers and their infants.

Dr.Camel's Conclusion

This study is a reminder that our understanding of medication safety is constantly evolving. Like the desert landscape that shifts over time, our understanding of the effects of medications on pregnant women and their babies can change as more research is conducted. Continued research is essential for developing safe and effective treatments for all individuals, including pregnant women living with HIV.

Date :
  1. Date Completed 2022-07-22
  2. Date Revised 2022-09-30
Further Info :

Pubmed ID

35858874

DOI: Digital Object Identifier

PMC9297643

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English

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