Paper Details

  1. Home
  2. Paper Details

Psychiatric adverse events in three phase III trials of eslicarbazepine acetate for focal seizures.

Author: AltalibHamada, BlumDavid, CantuDavid, GrinnellTodd, IkedoFábio, VieiraMariana, ZhangYi

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study evaluated risk factors for the development of psychiatric treatment-emergent adverse events (TEAEs) in patients taking eslicarbazepine acetate (ESL). ESL is an anti-seizure medication that is used to treat focal seizures. The researchers found that the risk of TEAEs was increased in patients with a history of psychiatric disorders.
Paper Details　
Original Abstract of the Article :
Eslicarbazepine acetate (ESL) is a once-daily (QD), oral anti-seizure medication for the treatment of focal (partial-onset) seizures. Here, we evaluate risk factors for the development of psychiatric treatment-emergent adverse events (TEAEs) in clinical trials of adjunctive ESL in adults with focal ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712463/

データ提供：米国国立医学図書館（NLM）

Evaluating Psychiatric Adverse Events in Eslicarbazepine Acetate Treatment

The development of new anti-seizure medications is a critical area of focus in neurology. This study investigates the risk factors for psychiatric treatment-emergent adverse events (TEAEs) associated with eslicarbazepine acetate (ESL), a novel anti-seizure medication for focal seizures. The authors analyzed data from three phase III clinical trials, examining the incidence and predictors of psychiatric TEAEs in patients receiving adjunctive ESL. The findings provide valuable insights into the potential psychiatric side effects of ESL, enabling clinicians to make informed decisions about its use and manage potential risks effectively.

A Comprehensive Assessment of Psychiatric Side Effects

The research provides a comprehensive evaluation of the psychiatric TEAEs associated with ESL. The study identifies potential risk factors for these adverse events, allowing clinicians to better predict and manage them, minimizing the impact on patient well-being.

Balancing Benefits and Risks in Epilepsy Treatment

This study underscores the importance of balancing the benefits and risks of epilepsy treatment. While ESL offers potential therapeutic benefits for patients with focal seizures, clinicians must remain vigilant about the potential for psychiatric side effects.

Dr.Camel's Conclusion

Like a camel carefully navigating through a desert landscape, clinicians must carefully consider the potential benefits and risks associated with ESL treatment. This study offers valuable insights into the psychiatric side effects of ESL, empowering clinicians to make informed decisions and manage potential risks effectively.

Date :
  1. Date Completed 2022-12-09
  2. Date Revised 2023-03-23
Further Info :

Pubmed ID

35908275

DOI: Digital Object Identifier

PMC9712463

Related Literature

Article Analysis
・Effects of eslicarbazepine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.