The Efficacy and Safety of Sacubitril-Valsartan for the Treatment of Heart Failure in Adults: A Meta-Analysis.

Author: FanHouDe, NingTing, TianQingshan, XiongZhiping, ZhengZhenZhong

Paper Details 
Original Abstract of the Article :
OBJECTIVE: The current meta-analysis reviews the different randomized controlled trials (RCTs) on the use of sacubitril-valsartan (SV) thoroughly and assesses its effectiveness and safety as a drug for heart failure. DATA SOURCES: Relevant articles for meta-analysis were searched from PubMed, MEDLI...See full text at original site
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引用元:
https://doi.org/10.1177/10600280221112158

データ提供:米国国立医学図書館(NLM)

Sacubitril-Valsartan: A Hopeful Treatment for Heart Failure

Heart failure, a debilitating condition affecting millions worldwide, requires effective treatment options to improve patient outcomes. Sacubitril-valsartan (SV), a combination medication, has shown promise in managing heart failure. This meta-analysis reviews various randomized controlled trials (RCTs) to assess the efficacy and safety of SV for the treatment of heart failure in adults.

A Promising Treatment for Heart Failure

The meta-analysis of ten RCTs involving 18,164 patients demonstrates that SV is effective in reducing hospitalization and cardiovascular mortality in patients with heart failure. The analysis shows that SV is associated with a statistically significant reduction in the number of patients experiencing heart-related events compared to control groups.

A New Era in Heart Failure Management

This research suggests that SV is a valuable addition to the arsenal of treatments for heart failure, offering potential for improved outcomes and quality of life for patients. The study highlights the importance of ongoing research to refine treatment strategies and optimize patient care for this complex and challenging condition.

Dr.Camel's Conclusion

Just as a camel's endurance and resilience allow it to navigate the vast and unforgiving desert, researchers are tirelessly searching for effective treatments for heart failure. This meta-analysis provides strong evidence for the efficacy and safety of sacubitril-valsartan, offering a beacon of hope for patients battling this debilitating condition. The findings underscore the ongoing efforts of researchers to improve the lives of those living with heart failure and provide them with a fighting chance.

Date :
  1. Date Completed 2023-03-09
  2. Date Revised 2023-03-14
Further Info :

Pubmed ID

35915995

DOI: Digital Object Identifier

10.1177/10600280221112158

Related Literature

SNS
PICO Info
in preparation
Languages

English

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