Effect of Galcanezumab on Total Pain Burden in Patients Who Had Previously Not Benefited from Migraine Preventive Medication (CONQUER Trial): A Post Hoc Analysis.

Author: AilaniJessica, AndrewsJeffrey Scott, RettigantiMallikarjuna, Tockhorn-HeidenreichAntje, WenzelRichard

Paper Details 
Original Abstract of the Article :
In evaluating therapies for migraine prevention, emphasis is placed on frequency and less attention is paid to duration or severity. Total pain burden (TPB) combines frequency, duration, and severity of migraine headache, and has the potential to further characterize the benefit of preventive treatm...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464727/

データ提供:米国国立医学図書館(NLM)

Galcanezumab: A New Hope for Migraine Prevention?

The [treatment of migraine] is a complex landscape, with [preventive medications] playing a key role. This post-hoc analysis explores the potential of [galcanezumab (GMB)] to reduce [total pain burden (TPB)] in individuals with [migraine] who had not responded to other preventative medications. The researchers sought to understand the impact of [GMB] on [TPB], combining [frequency, duration, and severity] of migraine headaches into a single measure.

Focusing on Total Pain Burden

This study highlights the importance of considering [TPB] as a key factor in [migraine management]. The authors suggest that focusing solely on [frequency] may not provide a complete picture of the [impact of migraine] on patients' lives. By taking a broader view, we can better understand the [overall burden of migraine] and tailor treatment strategies to address individual needs.

Potential for Improved Migraine Treatment

The results of this analysis suggest that [GMB] may offer a new approach to [migraine prevention] by reducing [TPB] in those who have not benefited from other medications. This finding provides valuable insights into the potential of [GMB] to improve [migraine control] and enhance [quality of life] for individuals struggling with this debilitating condition.

Dr. Camel's Conclusion

This research sheds light on a potentially new and promising approach to [migraine management]. It's like discovering a new oasis in the desert of [migraine research], offering hope for those seeking relief from this chronic condition. The focus on [TPB] provides a more comprehensive view of the [impact of migraine] and underscores the need for [personalized treatment] strategies.

Date :
  1. Date Completed 2022-09-13
  2. Date Revised 2023-01-29
Further Info :

Pubmed ID

35930126

DOI: Digital Object Identifier

PMC9464727

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.