Paper Details

  1. Home
  2. Paper Details

Immune non-interference and safety study of Vi-DT typhoid conjugate vaccine with a measles, mumps and rubella containing vaccine in 9-15 months old Nepalese infants.

Author: ChaudharyShipra, GiriBishnu Rath, GuptaBirendra Prasad, JoSue Kyoung, KanodiaPiush, KimBomi, KimDeok Ryun, KimHun, KimJerome H, KyungSeung-Eun, LeeYoonyeong, MojaresZenaida Reynoso, ParkHo Keun, ParkIl-Yeon, RaiGanesh Kumar, Reddy EJagadeesh, RyuJi Hwa, SahastrabuddheSushant, SalujaTarun, ShinJong Hoon, VemulaSridhar, WartelT Anh, YangJae Seung

Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study assessed the non-interference of Vi-DT TCV with a measles-containing vaccine in 9-15 months old healthy infants in Nepal.
Paper Details　
Original Abstract of the Article :
Typhoid fever is a common disease in developing countries especially in the Indian subcontinent and Africa. The available typhoid conjugate vaccines (TCV) have been found to be highly immunogenic in infants and children less than 2 years of age. Many countries are planning to adopt TCV in their rout...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.vaccine.2022.08.034

データ提供：米国国立医学図書館（NLM）

A Safe Oasis in the Desert of Childhood Vaccinations

Childhood vaccinations are essential for protecting young children from potentially life-threatening diseases. This study examines the safety and efficacy of a typhoid conjugate vaccine (Vi-DT TCV) when administered concurrently with a measles, mumps, and rubella (MMR) containing vaccine in Nepalese infants aged 9-15 months. The authors aimed to assess the potential for immune non-interference between these two vaccines, ensuring the continued effectiveness of both.

Navigating the Desert of Vaccine Safety

The study found that Vi-DT TCV did not interfere with the immune response to the measles containing vaccine. This finding is important for countries planning to include Vi-DT TCV in their routine vaccination programs, as it provides evidence for the safety and efficacy of administering these vaccines concurrently.

A Clear Path Towards Healthy Children

This research, like a well-marked trail through a desert landscape, provides reassurance about the safety and effectiveness of administering Vi-DT TCV alongside MMR containing vaccines. This study contributes to the growing body of evidence supporting the use of safe and effective vaccines to protect children around the world.

Dr.Camel's Conclusion

This study, like a refreshing oasis in the desert of childhood vaccinations, demonstrates the safety and effectiveness of combining Vi-DT TCV with MMR containing vaccines. It provides crucial information for countries seeking to protect their children from preventable diseases.

Date :
  1. Date Completed 2022-09-13
  2. Date Revised 2022-11-09
Further Info :

Pubmed ID

36064672

DOI: Digital Object Identifier

10.1016/j.vaccine.2022.08.034

Related Literature

Article Analysis
・Effects of mmr vaccine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.