Paper Details 
Original Abstract of the Article :
The cognitive adverse effects (AEs) of electroconvulsive therapy (ECT) limit the wider use of the treatment. These AEs can be attenuated by changing the way ECT is administered; however, such changes may reduce the response rate, the speed of response, or both. A recent systematic review and meta-an...See full text at original site
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引用元:
https://doi.org/10.4088/JCP.22f14668

データ提供:米国国立医学図書館(NLM)

Reconsidering the Benefits of Pharmacological Interventions for ECT-Induced Cognitive AEs

The [electroconvulsive therapy (ECT)] field is constantly striving to optimize this treatment modality, seeking to minimize [cognitive adverse effects (AEs)] while maximizing therapeutic benefits. This review critically examines the evidence for pharmacological interventions aimed at attenuating ECT-induced cognitive AEs. The authors analyzed data from [randomized controlled trials (RCTs)] investigating various interventions, including [acetylcholinesterase inhibitors, ketamine, memantine, liothyronine, anti-inflammatory treatments, and opioid receptor antagonists]. Their findings suggest potential benefits for some interventions, particularly [acetylcholinesterase inhibitors, ketamine, memantine, and liothyronine], in improving cognitive function. This review provides a valuable framework for understanding the potential benefits and limitations of pharmacological interventions for mitigating ECT-induced cognitive AEs.

Navigating the Complexities of ECT Treatment

The review's findings underscore the importance of a multi-faceted approach to ECT treatment. The authors' analysis highlights the need for careful consideration of the potential benefits and risks associated with different pharmacological interventions. It emphasizes the importance of individualized care, tailored to the specific needs and goals of each patient. The review also underscores the importance of further research to develop more effective strategies for minimizing ECT-induced cognitive AEs and maximizing therapeutic outcomes.

Balancing Benefits and Risks: A Desert Oasis in ECT Treatment

ECT treatment can feel like navigating a desert of uncertainty, with the potential for both therapeutic benefits and cognitive challenges. This review provides valuable insights into the potential role of pharmacological interventions in mitigating cognitive AEs. The authors' analysis suggests that carefully selected interventions, such as [acetylcholinesterase inhibitors, ketamine, memantine, and liothyronine], may help patients navigate the desert of ECT treatment and find a more comfortable oasis. I encourage individuals considering ECT to consult with their healthcare providers to discuss the potential benefits and risks of treatment and to explore options for minimizing cognitive AEs.

Dr.Camel's Conclusion

This review provides a critical analysis of the evidence for pharmacological interventions for attenuating ECT-induced cognitive AEs. The authors' insights are invaluable for informing clinical practice and guiding future research in this complex and rapidly evolving field. I encourage individuals considering ECT to discuss their concerns with their healthcare providers and to work together to develop a comprehensive treatment plan that addresses both therapeutic needs and potential cognitive side effects.

Date :
  1. Date Completed 2022-10-07
  2. Date Revised 2022-11-01
Further Info :

Pubmed ID

36198062

DOI: Digital Object Identifier

10.4088/JCP.22f14668

Related Literature

SNS
PICO Info
in preparation
Languages

English

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