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The safety and efficacy of low oral doses of cannabidiol: An evaluation of the evidence.

Author: ArnoldJonathon C, McCartneyDanielle, McGregorIain S, SuraevAnastasia

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Oral CBD doses of 300-400 mg per day showed evidence of reducing anxiety and having anti-addiction effects. Lower doses (less than 300 mg) may have some benefits, but more research is needed.
Paper Details　
Original Abstract of the Article :
Global interest in the non-intoxicating cannabis constituent, cannabidiol (CBD), is increasing with claims of therapeutic effects across a diversity of health conditions. At present, there is sufficient clinical trial evidence to support the use of high oral doses of CBD (e.g., 10-50 mg/kg) in...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841308/

データ提供：米国国立医学図書館（NLM）

Low Oral Doses of Cannabidiol: Evaluating Its Safety and Efficacy

Cannabidiol (CBD), a non-psychoactive compound found in cannabis, has gained considerable interest for its potential therapeutic effects. This review evaluates the evidence for the efficacy and safety of low oral doses of CBD in adult populations.

Evidence for Efficacy at Higher Doses

The review found that higher oral doses of CBD (e.g., 10-50 mg/kg) have demonstrated efficacy in treating intractable childhood epilepsies. However, the evidence for therapeutic benefits of lower oral doses is less consistent.

Exploring the Potential of Low-Dose CBD

The review suggests that while therapeutic benefits of CBD are more evident at doses greater than or equal to 300 mg, lower doses (less than 300 mg/day) may offer some benefits, particularly in reducing anxiety and promoting anti-addiction effects. Larger clinical trials are needed to confirm the potential of low-dose CBD.

Dr. Camel's Conclusion

This review highlights the complex and evolving landscape of CBD research. As a wise camel, I've learned that the desert of knowledge is vast and ever-changing. We must continue to explore the potential of CBD as a therapeutic agent, carefully considering the evidence and seeking to maximize its benefits while minimizing potential risks.

Date :
  1. Date Completed 2023-01-19
  2. Date Revised 2023-02-02
Further Info :

Pubmed ID

36259271

DOI: Digital Object Identifier

PMC9841308

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English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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