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A multicenter, randomized, double-blind, placebo-controlled, crossover trial to evaluate the efficacy and safety of zolmitriptan nasal spray for the acute treatment of migraine in patients aged 6 to 11 years, with an open-label extension.
Author: McVigeJennifer, VisserHester, YonkerMarcy E, ZeitlinLeonid
Original Abstract of the Article :
OBJECTIVE: To evaluate the efficacy and safety of zolmitriptan nasal spray (ZNS) in the acute treatment of migraine headache in patients aged 6 to 11 years. BACKGROUND: Triptans have demonstrated efficacy in adults, but pediatric studies of these agents have largely failed and there are few triptan...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/head.14391
データ提供:米国国立医学図書館(NLM)
Zolmitriptan Nasal Spray: A New Hope for Pediatric Migraine?
This study explores the efficacy and safety of zolmitriptan nasal spray (ZNS) in treating migraine headaches in children aged 6 to 11 years. The researchers conducted a randomized, double-blind, placebo-controlled trial with an open-label extension to evaluate the effectiveness of ZNS in this young patient population. While triptans have shown promise in adults, pediatric studies have been limited, and there are few triptan options specifically for children.
Zolmitriptan Nasal Spray: A Potential Treatment for Pediatric Migraine
The study, while terminated early due to slow enrollment, showed promising results, with ZNS achieving pain-free status at 2 hours in a significant number of patients. The study also demonstrated that ZNS was well-tolerated in this pediatric population, with few treatment-related adverse events.
Navigating Pediatric Migraine: A Promising Treatment Option
This research offers a glimmer of hope for children suffering from migraine headaches. While further research is needed to confirm these findings, the study suggests that ZNS could be a valuable treatment option for pediatric patients. It is important to consult with a healthcare professional to determine the best treatment plan for individual children.
Dr.Camel's Conclusion
Just as a camel navigates the desert with resilience and determination, children battling migraine headaches deserve effective treatment options. This research, while in its early stages, provides a hopeful glimpse into the potential of zolmitriptan nasal spray to alleviate the pain and suffering of young migraine sufferers.
Date :
- Date Completed 2022-10-28
- Date Revised 2022-12-02
Further Info :
Related Literature
English
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