Epidemiology, etiology and clinical associations of congenital heart disease identified during congenital rubella syndrome surveillance.

Author: DeoraSurender, NagVijaya Lakshmi, PriyankaPriyanka, SinghKuldeep, VyasVaruna

Paper Details 
Original Abstract of the Article :
BACKGROUND: Congenital heart disease (CHD) is a common congenital malformation. Antenatal rubella infection in the mother and genetic defects are important causes to which CHD are attributed. Exact contribution of antenatal rubella infection or genetic causes to CHD is still unknown. OBJECTIVE: To ...See full text at original site
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引用元:
https://doi.org/10.1093/tropej/fmac089

データ提供:米国国立医学図書館(NLM)

Congenital Heart Disease and Congenital Rubella Syndrome: A Challenging Link

Congenital heart disease (CHD), a birth defect affecting the heart, can be likened to a desert oasis where the water source is disrupted, causing significant challenges for individuals. This study explores the connection between CHD and congenital rubella syndrome (CRS), a viral infection that can lead to birth defects. The researchers, like detectives investigating a complex case, sought to understand the link between these two conditions.

The study, conducted in Western Rajasthan, India, found that CRS contributed to 8.5% of the CHD cases observed. The researchers also found that CRS was associated with a wide range of CHD defects, highlighting the varied impact of this viral infection. This research sheds light on the importance of preventing rubella infection during pregnancy to protect infants from this potentially devastating condition.

Understanding the Impact of Rubella Infection

This study provides valuable insights into the impact of rubella infection on fetal development. The findings suggest that rubella, like a desert sandstorm, can have a significant and unpredictable impact on the developing heart, leading to a variety of CHD defects. This research emphasizes the importance of vaccination programs to prevent rubella infection and protect future generations from this preventable condition.

Preventing Congenital Heart Disease: A Collective Effort

This study underscores the importance of a global effort to eliminate rubella. The researchers' findings, like a map guiding us through a challenging desert, demonstrate the link between rubella infection and CHD, highlighting the need for robust vaccination programs. By working together, like a caravan traveling across the desert, we can reduce the incidence of CRS and protect infants from this preventable condition, creating a healthier future for all.

Dr. Camel's Conclusion

This study sheds light on the complex relationship between CHD and CRS, revealing the significant impact of rubella infection on fetal development. Like a desert oasis, where the water source is crucial for survival, the heart is vital for life. This research emphasizes the importance of preventing rubella infection, through vaccination and other preventative measures, to protect future generations from this potentially devastating condition. Let us all work together, like a caravan united in purpose, to create a world where every child has a healthy heart and a chance to thrive.

Date :
  1. Date Completed 2022-11-01
  2. Date Revised 2022-11-20
Further Info :

Pubmed ID

36306124

DOI: Digital Object Identifier

10.1093/tropej/fmac089

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English

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