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Effectiveness and safety of dolutegravir and raltegravir for treating children and adolescents living with HIV: a systematic review.

Author: CastroHannah, CollinsIntira Jeannie, JessonJulie, JuddAli, LeroyValériane, MilanziEdith, O'RourkeJohn, PenazzatoMartina, RenaudFrançoise, TownsendClaire L, VicariMarissa

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This systematic review assesses the effectiveness and safety of dolutegravir and raltegravir, two integrase strand transfer inhibitors, in children and adolescents living with HIV. Dolutegravir and raltegravir are increasingly used in pediatric HIV treatment, but more information is needed about their efficacy and safety in this population. This review aims to provide evidence-based recommendations for the use of these medications in children and adolescents.
Paper Details　
Original Abstract of the Article :
Globally about 1.7 million children were living with HIV in 2020. Two integrase strand transfer inhibitors, dolutegravir and raltegravir, are increasingly used in children. We conducted a systematic review to assess the effectiveness and safety of dolutegravir and raltegravir in children and adolesc...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663860/

データ提供：米国国立医学図書館（NLM）

A Comprehensive Look at Dolutegravir and Raltegravir for Young HIV Patients

The world of medicine is constantly evolving, particularly in the realm of HIV treatment. This research dives deep into the effectiveness and safety of dolutegravir and raltegravir for children and adolescents living with HIV. Imagine a vast desert, with each grain of sand representing a potential treatment option. This research carefully sifts through the sand, using a systematic review to uncover the most promising avenues for these medications. The study found that these integrase strand transfer inhibitors are gaining traction, offering a ray of hope for young patients. The study, much like a desert oasis, provides valuable insights into the effectiveness and safety of these medications, offering a beacon of hope for families navigating this challenging terrain.

Key Findings: A Positive Outlook

The study revealed positive results regarding the effectiveness and safety of dolutegravir and raltegravir for children and adolescents living with HIV. This is like discovering a new source of freshwater in a parched desert. It's a promising sign for future treatment strategies.

Understanding the Implications: A Lifelong Journey

This research provides crucial information for doctors and families dealing with HIV in children. It's like finding a map through a labyrinthine desert. It helps navigate the complexities of treatment and provides a roadmap for a healthy future.

Dr. Camel's Conclusion

This research provides an important contribution to the field of HIV treatment. It shines a light on the potential of dolutegravir and raltegravir in treating young patients. Like a desert explorer discovering a hidden oasis, this study offers a source of optimism and hope.

Date :
  1. Date Completed 2022-11-16
  2. Date Revised 2023-03-15
Further Info :

Pubmed ID

36377082

DOI: Digital Object Identifier

PMC9663860

Related Literature

Article Analysis
・Side Effects of raltegravir
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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