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Placebo Response and Media Attention in Randomized Clinical Trials Assessing Cannabis-Based Therapies for Pain: A Systematic Review and Meta-analysis.

Author: BloméSebastian, FustJens, GedinFilip, JensenKarin, LalouniMaria, PonténMoa, RaquetteAndreé, ThompsonWilliam H, Vadenmark LundquistViktor

Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study suggests that positive expectations may play a role in the effectiveness of medicinal cannabis for persistent pain, as the superiority of cannabinoids over placebo in clinical trials is limited.
Paper Details　
Original Abstract of the Article :
Persistent pain is a common and disabling health problem that is often difficult to treat. There is an increasing interest in medicinal cannabis for treatment of persistent pain; however, the limited superiority of cannabinoids over placebo in clinical trials suggests that positive expectations may ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706362/

データ提供：米国国立医学図書館（NLM）

The Placebo Effect: A Powerful Force in Cannabis-Based Pain Relief

The use of cannabis-based therapies for pain management is a rapidly growing area of interest. This study examines the role of the placebo effect in clinical trials evaluating cannabis-based therapies for persistent pain.

Beyond the Plant: Understanding the Placebo Effect

Researchers explored the possibility that positive expectations, often associated with the use of cannabis, might contribute to improvements observed in clinical trials. The study found limited superiority of cannabinoids over placebo in clinical trials, suggesting that the placebo effect might be a significant factor in perceived pain relief.

Navigating the Complexities of Pain Management

This research highlights the importance of understanding the complex interplay between psychological factors, expectations, and the effects of medications. It emphasizes the need for rigorous research and careful consideration of the placebo effect when evaluating the effectiveness of cannabis-based therapies for pain.

Dr.Camel's Conclusion

As a researcher, I am always fascinated by the powerful influence of the mind on the body. This study reminds us that the placebo effect is a real phenomenon with significant implications for pain management. It's like a mirage in the desert – what appears to be a refreshing oasis might be an illusion. We must be cautious in attributing all improvements solely to the medication itself and acknowledge the potential role of the placebo effect.
Date :
  1. Date Completed 2022-11-30
  2. Date Revised 2022-12-15
Further Info :

Pubmed ID

36441553

DOI: Digital Object Identifier

PMC9706362

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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