Paper Details 
Original Abstract of the Article :
PURPOSE: To describe a case of unilateral retinal arterial occlusive vasculitis after multiple intravitreal brolucizumab (IVBr) treatments for diabetic macular edema (DME). OBSERVATIONS: A 68-year-old Japanese woman who had a 3-year history of insulin-dependent diabetes mellitus presented with decr...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826871/

データ提供:米国国立医学図書館(NLM)

Brolucizumab and Retinal Vasculitis: A Storm in the Eye

The human eye, a delicate and intricate organ, is like a precious pearl in the desert. This study explores the potential complications of brolucizumab, an anti-VEGF drug, on the retinal vasculature. Brolucizumab is used to treat diabetic macular edema (DME), a condition that can lead to vision loss.

The study describes a case of a patient who developed retinal arterial occlusive vasculitis after receiving multiple intravitreal brolucizumab injections for DME. Retinal arterial occlusive vasculitis is a serious condition that can lead to permanent vision loss. The researchers meticulously documented the patient's case, noting the progression of ocular inflammation and vasculitis after brolucizumab treatment. The case report highlights the importance of monitoring patients for potential complications after brolucizumab treatment.

Navigating the Desert of Potential Complications

This case study serves as a reminder that even seemingly safe medical interventions can have unexpected consequences. The research highlights the potential risk of retinal arterial occlusive vasculitis with brolucizumab treatment, emphasizing the need for careful monitoring and prompt treatment. The findings also suggest that topical steroid administration may help manage intraocular inflammation and subsequent vasculitis, but further research is needed to determine the effectiveness of this approach.

Keep Your Eyes Open

This research underscores the importance of vigilant monitoring for potential complications after brolucizumab treatment. Just as a camel must constantly scan the horizon for dangers, so too must healthcare professionals remain alert to the potential for adverse effects. This research also highlights the need for further research to better understand the mechanisms by which brolucizumab can trigger retinal vasculitis and to develop more effective treatment strategies.

Dr. Camel's Conclusion

This research serves as a reminder that even in the field of medicine, with its vast knowledge and technological advancements, there are still unexpected challenges. The case report highlights the potential for brolucizumab to induce retinal arterial occlusive vasculitis, a serious condition that can lead to vision loss. It underscores the importance of vigilance, careful monitoring, and prompt treatment to minimize the risk of complications. This research underscores the need for ongoing research in ophthalmology to better understand and manage the complexities of the human eye.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-01-13
Further Info :

Pubmed ID

36632338

DOI: Digital Object Identifier

PMC9826871

Related Literature

SNS
PICO Info
in preparation
Languages

English

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