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Comparison of diflunisal and an aspirin-codeine combination in the management of patients having one-visit endodontic therapy.

Author: BolanosO R, EspositoJ V, FurstM L, KorenL Z, MorseD R, YesilsoyC

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Diflunisal was more effective than aspirin with codeine in controlling pain after endodontic treatment. It was also better tolerated, with fewer patients experiencing side effects.
Paper Details　
Original Abstract of the Article :
One hundred seventy-nine patients with asymptomatic or mildly symptomatic endodontic disease had single-visit therapy and were given either diflunisal (n = 94) or aspirin with codeine (n = 85) to control posttreatment pain. In this open-label, randomized study, diflunisal was judged superior to the ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/3664553

データ提供：米国国立医学図書館（NLM）

Diflunisal vs. Aspirin-Codeine: A Battle in the Desert of Endodontic Pain

The field of [endodontic therapy] often involves managing [posttreatment pain] which can be a significant source of discomfort for patients. This study compares the effectiveness of [diflunisal] and [aspirin-codeine] in controlling [posttreatment pain] following [single-visit endodontic therapy]. The authors conducted an [open-label, randomized] trial to evaluate the analgesic efficacy and side effect profiles of these drugs in [179 patients] undergoing this procedure.

Diflunisal Emerges as a Winner

The results of this study suggest that [diflunisal] may be superior to [aspirin-codeine] in managing [posttreatment pain] following [single-visit endodontic therapy]. Patients receiving [diflunisal] generally experienced [shorter duration of pain] and [fewer doses] of medication compared to those receiving [aspirin-codeine]. Moreover, [diflunisal] had a lower incidence of [side effects].

Navigating the Desert of Endodontic Pain Management

Endodontic treatment often involves navigating a desert of potential pain and discomfort. This study suggests that [diflunisal] may offer a more effective and well-tolerated solution for managing [posttreatment pain], compared to [aspirin-codeine]. However, it's important to consult with a dentist or dental professional to determine the best pain management strategy based on individual needs and preferences.

Dr.Camel's Conclusion

This study highlights the potential benefits of [diflunisal] over [aspirin-codeine] for managing [posttreatment pain] following [single-visit endodontic therapy]. While further research is needed to confirm these findings, [diflunisal] appears to be a promising analgesic option for patients seeking effective and well-tolerated pain relief.

Date :
  1. Date Completed 1987-12-17
  2. Date Revised 2020-12-09
Further Info :

Pubmed ID

3664553

DOI: Digital Object Identifier

3664553

Related Literature

Article Analysis
・Side Effects of diflunisal
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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