Lorcaserin and phentermine exert anti-obesity effects with modulation of the gut microbiota.

Author: JeonSonghee, KimHojun, NamYoung-Do, ShinNa Rae, SongEun-Ji

Paper Details 
Original Abstract of the Article :
Although drugs have been reported to modulate the gut microbiota, the effects of anti-obesity drugs on the gut microbiota remain unclear. Lorcaserin (LS) and phentermine (PT) are commonly used anti-obesity drugs. However, to our best knowledge, no studies have simultaneously assessed the effects of ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849812/

データ提供:米国国立医学図書館(NLM)

The Gut-Brain Connection: Anti-Obesity Drugs and the Microbiome

Obesity is a growing global health concern, and scientists are constantly searching for new and effective treatments. This research investigates the impact of two commonly used anti-obesity drugs, lorcaserin (LS) and phentermine (PT), on the gut microbiota, the complex community of bacteria living in our intestines. The researchers found that both drugs modulated the gut microbial composition, suggesting a potential link between the gut microbiome and the anti-obesity effects of these medications.

Beyond Weight Loss: The Microbiome's Role in Health and Well-being

This study provides further evidence for the critical role of the gut microbiome in health and disease. The researchers discovered that LS and PT, through their modulation of the gut microbiota, could potentially contribute to weight loss and improved metabolic health. This research encourages us to consider the complex interplay between our gut bacteria and our overall well-being.

A New Frontier in Obesity Treatment: Harnessing the Power of the Microbiome

This research opens up exciting new avenues for the development of anti-obesity therapies. By understanding the relationship between anti-obesity drugs and the gut microbiome, scientists may be able to develop more targeted and effective treatments that address both weight loss and overall metabolic health. This study serves as a reminder that the gut microbiome is a powerful force that plays a significant role in our health.

Dr. Camel's Conclusion

This study, like a desert oasis teeming with life, reminds us of the critical role that the gut microbiome plays in our health. The findings suggest that anti-obesity drugs may be working in part by modulating the gut microbiota, opening up exciting new possibilities for the development of more effective and targeted treatments.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-02-01
Further Info :

Pubmed ID

36687627

DOI: Digital Object Identifier

PMC9849812

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.