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[Adverse drug reactions to multiple antibiotics].

Author: ErnstGlenda, KotLilian, ScolariMariano, TrovatoDaiana

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
English AbstractA summary of a research paper/publication written in English for a wider audience.

Overview

This case report describes a woman diagnosed with multisensitive Staphylococcus aureus endocarditis who experienced adverse reactions to five different antibiotics in two hospitalizations. This case may be an example of multidrug intolerance syndrome, an under-reported entity, or an as-yet uncharacterized condition.
Paper Details　
Original Abstract of the Article :
Adverse reaction reporting is essential to understand the actual safety of marketed medicines. There are cases of patients with multidrug intolerance syndrome, an under-reported entity, which can occur when adverse reactions to more than two pharmacologically unrelated drugs occur in the same patien...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
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引用元：
https://pubmed.ncbi.nlm.nih.gov/36774615

データ提供：米国国立医学図書館（NLM）

Multidrug Intolerance Syndrome: A Case Report

[Multidrug intolerance syndrome] is a rare condition characterized by adverse reactions to multiple pharmacologically unrelated drugs. This case report describes a patient who experienced adverse reactions to five different antibiotics during two hospitalizations, highlighting the challenges associated with managing this complex syndrome.

Adverse Reactions to Multiple Antibiotics

The patient, diagnosed with [multisensitive Staphylococcus aureus endocarditis], experienced a series of adverse reactions to [cefazolin, vancomycin, daptomycin, linezolid, and cotrimoxazole]. These reactions involved different organ systems, including the hematologic, renal, hepatic, and cardiovascular systems. This case highlights the complexity of multidrug intolerance syndrome and the importance of carefully considering individual patient factors when choosing antibiotic therapy.

Understanding and Managing Multidrug Intolerance Syndrome

This case report emphasizes the need for greater awareness and understanding of multidrug intolerance syndrome. Further research is needed to identify the underlying mechanisms and develop more effective strategies for managing this challenging condition. The case also highlights the importance of vigilant monitoring and prompt intervention to minimize the risk of serious complications.

Dr.Camel's Conclusion

Think of multidrug intolerance syndrome as a desert with hidden traps: what seems like a safe path can suddenly lead to unexpected dangers. This case report reminds us that treating patients with this syndrome requires careful navigation and a thorough understanding of the potential risks. We need to continue exploring this challenging landscape to find safer and more effective ways to care for patients with multidrug intolerance syndrome.

Date :
  1. Date Completed 2023-02-14
  2. Date Revised 2023-02-14
Further Info :

Pubmed ID

36774615

DOI: Digital Object Identifier

36774615

SNS
PICO Info
in preparation
Languages

Spanish

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