Adjunctive cenobamate in highly active and ultra-refractory focal epilepsy: A "real-world" retrospective study.

Author: BreenAnnette, ColleranNiamh, DelantyNorman, DoyleMichael, El-NaggarHany, LigganBrenda, MoloneyPatrick B, MunteanuTudor, MurphySinead, Peña-CeballosJavier, Widdess-WalshPeter

Paper Details 
Original Abstract of the Article :
Recent clinical trials have shown that cenobamate substantially improves seizure control in focal-onset drug-resistant epilepsy (DRE). However, little is known about cenobamate's performance in highly active (≥20 seizures/month) and ultra-refractory focal epilepsy (≥6 failed epilepsy treatments, inc...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1111/epi.17549

データ提供:米国国立医学図書館(NLM)

Cenobamate: A Potential Oasis for Highly Active and Ultra-Refractory Epilepsy

The world of epilepsy treatment is a complex and often challenging desert, with many patients struggling to find effective medications. This study investigates the efficacy and tolerability of cenobamate, a new antiseizure medication, in a 'real-world' cohort of patients with highly active and ultra-refractory focal epilepsy. It's like searching for a hidden oasis that can provide relief from the relentless storms of seizures. The researchers found that cenobamate showed promise in improving seizure control in this challenging patient population. This is like discovering a hidden spring in the desert that offers a source of hope and relief. However, the study also highlights the need for further research to understand cenobamate's long-term effects and optimize its use in this complex population.

Cenobamate: A Potential Hope for Severe Epilepsy

This study provides evidence that cenobamate may be effective in controlling seizures in patients with highly active and ultra-refractory epilepsy. This is like finding a rare and resilient plant in the desert that can thrive in harsh conditions. The authors emphasize the need for careful monitoring and ongoing research to ensure that this promising medication can be used safely and effectively to improve the lives of those living with epilepsy.

Navigating the Desert of Epilepsy

Epilepsy is a complex and challenging condition, and finding the right medication can be a long and arduous journey. This study highlights the importance of ongoing research and development of new medications for those with severe epilepsy. It's like exploring a vast and unforgiving desert, seeking effective treatments to alleviate the suffering and improve the quality of life of patients.

Dr.Camel's Conclusion

This study explores the potential of cenobamate for patients with highly active and ultra-refractory focal epilepsy, offering a glimmer of hope in the vast desert of epilepsy treatment. The findings suggest that cenobamate may be a valuable tool for improving seizure control, but further research is needed to optimize its use and ensure its long-term safety and efficacy.

Date :
  1. Date Completed 2023-05-11
  2. Date Revised 2023-05-14
Further Info :

Pubmed ID

36790345

DOI: Digital Object Identifier

10.1111/epi.17549

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.