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Cocktail effects of emerging contaminants on zebrafish: Nanoplastics and the pharmaceutical diphenhydramine.

Author: AmorimMónica J B, BarretoAngela, CalistoVânia, MariaVera L, RochaLuciana S, SantosJoana

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigated the toxicity of polystyrene nanoplastics (NPLs) combined with diphenhydramine (DPH) to zebrafish embryos. The results demonstrated a synergistic interaction between NPLs and DPH, increasing toxicity compared to individual exposures. This emphasizes the importance of considering NPLs as potential carriers of other contaminants in environmental risk assessments.
Paper Details　
Original Abstract of the Article :
Nanoplastics (NPLs) became ubiquitous in the environment, from the air we breathe to the food we eat. One of the main concerns about the NPLs risks is their role as carrier of other environmental contaminants, potentially increasing their uptake, bioaccumulation and toxicity to the organisms. Theref...See full text at original site
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引用元：
https://doi.org/10.1016/j.impact.2023.100456

データ提供：米国国立医学図書館（NLM）

Nanoplastics and Diphenhydramine: A Toxic Cocktail in the Environment

The environment is a delicate balance, and even small changes can have significant consequences. This study delves into the potential synergistic effects of nanoplastics (NPLs) and the pharmaceutical diphenhydramine (DPH) on zebrafish embryos. The study uses zebrafish as a model organism to investigate the combined toxicity of these two substances, shedding light on the potential dangers of environmental pollution. This research is like exploring a desert ecosystem, uncovering the hidden dangers of seemingly harmless substances.

A Toxic Cocktail

The study reveals that the combination of NPLs and DPH is significantly more toxic than either substance alone. This finding, like a venomous scorpion lurking in a desert oasis, highlights the hidden dangers of environmental pollution.

Protecting Our Environment

This research underscores the importance of considering the potential synergistic effects of environmental contaminants. Just as a desert traveler must be aware of the dangers of the terrain, we must be vigilant about the impact of pollution on our environment.

Dr. Camel's Conclusion

This study serves as a wake-up call, reminding us of the potential dangers of environmental pollution. It highlights the importance of reducing our reliance on single-use plastics and addressing the widespread presence of pharmaceuticals in our environment.

Date :
  1. Date Completed 2023-06-05
  2. Date Revised 2023-06-07
Further Info :

Pubmed ID

36841353

DOI: Digital Object Identifier

10.1016/j.impact.2023.100456

Related Literature

Article Analysis
・Effects of diphenhydramine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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