Thrombocytopenia during avacopan administration: A case report.

Author: AkagiYuichiro, AndoFumiaki, FujikiTamami, HaniokaAsami, IimoriSoichiro, MandaiShintaro, MoriKatsuo, MoriTakayasu, MoriYutaro, MorimotoNobuhisa, NaitoShotaro, SakaiKeigo, ShiojiShingo, SoharaEisei, SusaKoichiro, UchidaShinichi, WatanabeHatsumi, YamamuraAyumi

Paper Details 
Original Abstract of the Article :
Avacopan is a novel C5a receptor antagonist recently approved for the treatment of microscopic polyangiitis and granulomatosis with polyangiitis. To our knowledge, thrombocytopenia induced by avacopan has not been reported. We report a case of a 78-year-old man with microscopic polyangiitis who deve...See full text at original site
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引用元:
https://doi.org/10.1111/1756-185X.14645

データ提供:米国国立医学図書館(NLM)

A New Oasis in Vasculitis Treatment: Avacopan and a Case of Thrombocytopenia

The desert of vasculitis treatment is a challenging terrain, requiring a careful exploration of new therapeutic approaches. This case report, like a lone traveler venturing into uncharted territory, describes the experience of a patient with [microscopic polyangiitis] who developed thrombocytopenia during treatment with [avacopan], a novel C5a receptor antagonist. The doctors, like seasoned explorers, meticulously documented the patient's condition and the potential role of avacopan in the development of thrombocytopenia. This case highlights the importance of postmarketing surveillance to identify potential side effects of new medications.

Navigating the Desert of New Medications

This case report, like a warning sign in a desert, underscores the importance of careful monitoring of new medications. While avacopan shows promise in treating vasculitis, this case reminds us that even the most promising treatments can have unexpected side effects. Postmarketing surveillance is crucial in ensuring the safety and efficacy of new medications.

The Importance of Vigilance in Healthcare

This case report emphasizes the importance of vigilance in healthcare. It's a reminder that even as we explore new oases of treatment, we must remain alert to potential dangers in the desert of medical practice. Careful monitoring and open communication between patients and doctors are crucial in ensuring the safety and well-being of everyone.

Dr. Camel's Conclusion

This case report underscores the crucial need for ongoing vigilance in the desert of healthcare. While avacopan shows promise in treating vasculitis, this case reminds us that even the most promising treatments can have unexpected side effects. By meticulously documenting and analyzing these cases, we can ensure a safer journey for patients and continue to improve our understanding of new medications.

Date :
  1. Date Completed 2023-10-23
  2. Date Revised 2023-10-23
Further Info :

Pubmed ID

36880594

DOI: Digital Object Identifier

10.1111/1756-185X.14645

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Languages

English

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