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Management of noncytotoxic extravasation injuries: A focused update on medications, treatment strategies, and peripheral administration of vasopressors and hypertonic saline.

Author: KiserTyree H, MacLarenRobert, MuellerScott W, ReynoldsPaul M, StefanosSylvia S

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review explores extravasation, the leakage of intravenous solutions into surrounding tissues. It discusses the various factors influencing extravasation, including drug properties, infusion techniques, and patient-related risk factors. The review also examines the physiochemical causes of tissue injury, including vasoconstriction, pH-mediated, osmolar-mediated, and cytotoxic mechanisms. It further highlights pharmacological antidotes and management strategies, emphasizing a multidisciplinary approach for early detection, treatment, and surgical referral when necessary.
Paper Details　
Original Abstract of the Article :
Extravasation is the leakage of intravenous solutions into surrounding tissues, which can be influenced by drug properties, infusion techniques, and patient-related risk factors. Although peripheral administration of vesicants may increase the risk of extravasation injuries, the time and resources r...See full text at original site
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引用元：
https://doi.org/10.1002/phar.2794

データ提供：米国国立医学図書館（NLM）

Navigating the Extravasation Desert: A Guide to Treatment Strategies

Extravasation is like a sudden desert storm that can strike during intravenous therapy, causing leakage of fluids into surrounding tissues. It's a complex and potentially dangerous situation, like a sandstorm that can obscure your path. This research provides an update on our understanding of extravasation injuries, focusing on emerging strategies for treatment and prevention.

Finding Your Way Through the Extravasation Storm

This research highlights the importance of a multidisciplinary approach to extravasation management, much like a caravan navigating a treacherous desert. It emphasizes the role of early detection, prompt treatment, and timely surgical referral when needed. The study also explores the role of different medications, such as phentolamine and terbutaline, in reversing the effects of vasoconstriction, and hyaluronidase in dispersing the extravasated fluids.

Staying Prepared for the Desert Storms

Understanding the causes of extravasation, including vasoconstriction, pH-mediated, osmolar-mediated, and cytotoxic mechanisms, is crucial to prevention. This research helps us better understand the factors that contribute to extravasation and identify ways to minimize risks. It's like understanding the weather patterns in the desert to avoid being caught in a sandstorm. By staying informed and prepared, we can navigate these challenges effectively.

Dr.Camel's Conclusion

This research sheds light on the complex world of extravasation injuries. It helps us understand the causes, treatment options, and the importance of a proactive approach to preventing and managing these challenging situations. Just as a seasoned desert traveler is prepared for the unexpected, healthcare providers need to be equipped to handle extravasation effectively, ensuring the safety and well-being of patients.
Date :
  1. Date Completed 2023-04-21
  2. Date Revised 2023-05-03
Further Info :

Pubmed ID

36938775

DOI: Digital Object Identifier

10.1002/phar.2794

SNS
PICO Info
in preparation
Languages

English

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