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Use of biologics for the management of Crohn's disease: IG-IBD technical review based on the GRADE methodology.

Author: ArmuzziAlessandro, BonovasStefanos, FestaStefano, MacalusoFabio Salvatore, OrlandoAmbrogio, PansieriClaudia, PapiClaudio, PiovaniDaniele, PuglieseDaniela

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Practice GuidelineGuidelines and recommendations for the diagnosis and treatment of specific medical conditions in medical practice.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This technical review systematically searched and identified the current evidence, synthesized it using meta-analytic methodology, appraised its quality, and concisely presented it, thus forming the basis for developing clinical practice recommendations on the use of biologic treatments in adult patients with CD.
Paper Details　
Original Abstract of the Article :
The therapeutic armamentarium for the management of Crohn's disease (CD) is rapidly expanding. Several biologic therapies (e.g. infliximab, adalimumab, vedolizumab, and ustekinumab) have been regulatory approved, and there is considerable practice variability in the treatment of patients with CD. Th...See full text at original site
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引用元：
https://doi.org/10.1016/j.dld.2023.02.019

データ提供：米国国立医学図書館（NLM）

Biologics for the Management of Crohn's Disease

This study delves into the complex and challenging landscape of [Crohn's disease (CD)], a chronic inflammatory bowel disease that can be as debilitating as a sandstorm. The researchers, like intrepid explorers searching for a cure, investigate the use of [biologic therapies] as a potential treatment option. They aim to navigate the vast terrain of CD and find a path towards effective management and improved patient outcomes.

Biologic Therapies Offer Promise for Crohn's Disease

The study found that [biologic therapies] have shown promise in the management of CD. This discovery is like finding a hidden oasis in the desert, offering a much-needed source of relief and hope for patients struggling with this debilitating disease.

Potential for Personalized Treatment Approaches

This study emphasizes the importance of personalized treatment approaches for CD, taking into account the unique needs and challenges faced by each individual. It's like understanding the diverse ecosystems within a desert and tailoring strategies to optimize the survival and well-being of each unique species.

Dr.Camel's Conclusion

This study provides a comprehensive review of the use of biologics in the management of Crohn's disease, highlighting the potential of these therapies in offering a more effective and personalized approach to treatment. This research is like a compass guiding healthcare professionals through the complex landscape of CD, paving the way for better patient outcomes and improved quality of life.

Date :
  1. Date Completed 2023-05-29
  2. Date Revised 2023-07-20
Further Info :

Pubmed ID

36964060

DOI: Digital Object Identifier

10.1016/j.dld.2023.02.019

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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