Paper Details 
Original Abstract of the Article :
Idiopathic inflammatory myopathies (IIMs) are autoimmune disorders characterized by symmetric proximal muscle weakness and chronic inflammation, with an increased risk of morbidity and mortality. The current standard of care includes traditional immunosuppressive pharmacotherapies; however, some pat...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140234/

データ提供:米国国立医学図書館(NLM)

Acthar Gel for the Treatment of Myositis: A Narrative Review

This narrative review explores the use of Acthar® Gel (repository corticotropin injection) as a potential treatment for myositis, a group of autoimmune disorders characterized by muscle inflammation and weakness. The researchers reviewed the current evidence on the safety and efficacy of Acthar Gel for the treatment of dermatomyositis (DM) and polymyositis (PM), two subgroups of myositis. They aimed to provide a comprehensive overview of the available data and highlight the potential benefits of Acthar Gel for patients with refractory myositis.

The review suggests that Acthar Gel may be effective in treating refractory DM and PM. Acthar Gel's mechanism of action involves both steroidogenesis and immunomodulatory effects, suggesting its potential to provide therapeutic benefits in patients who do not respond to traditional immunosuppressive therapies. The review emphasizes the need for further clinical trials to evaluate the long-term safety and efficacy of Acthar Gel in the treatment of myositis.

Acthar Gel: A Potential Treatment for Refractory Myositis

This review, like a camel seeking a hidden oasis in the desert of myositis, explores the potential of Acthar Gel as a therapeutic option for patients with refractory disease. The review highlights the need for further research to validate its efficacy and safety in the long-term.

Navigating the Desert of Myositis: Exploring New Treatment Options

Myositis, like a harsh desert environment, can be a challenging condition to manage. This narrative review offers a glimpse of hope by exploring the potential of Acthar Gel as a treatment option for refractory myositis. The review encourages further research to determine the long-term efficacy and safety of this medication in treating this debilitating disorder.

Dr.Camel's Conclusion

This narrative review, like a camel caravan traversing the vast desert of myositis research, explores the potential of Acthar Gel as a treatment option for refractory dermatomyositis and polymyositis. While further research is needed to confirm its long-term efficacy and safety, Acthar Gel offers a potential new avenue for treating patients with these challenging conditions.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-05-01
Further Info :

Pubmed ID

36966453

DOI: Digital Object Identifier

PMC10140234

SNS
PICO Info
in preparation
Languages

English

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