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Vascular effects of biologic and targeted synthetic antirheumatic drugs approved for rheumatoid arthritis: a systematic review.

Author: DimovaMaria, GeorgievTsvetoslav, GerganovGeorgi, ShivachevaTanya

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This study aims to investigate the impact of medications used to treat rheumatoid arthritis (RA) on the risk of cardiovascular disease (CVD). Because RA is linked to increased inflammation, and the medications used to treat RA can affect the immune system, the study seeks to understand how these medications might influence the risk of heart problems in people with RA. The abstract does not provide specific results, only the research question. Therefore, we cannot provide a summary of the study's findings.
Paper Details　
Original Abstract of the Article :
Rheumatoid arthritis (RA) increases the risk of cardiovascular disease (CVD), with inflammation playing a key role. Biologic and targeted synthetic drugs used to treat RA can induce systemic immunomodulation and may have pleiotropic effects on vascular function, making it crucial to investigate thei...See full text at original site
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引用元：
https://doi.org/10.1007/s10067-023-06587-8

データ提供：米国国立医学図書館（NLM）

Vascular Effects of Biologic and Targeted Synthetic Anti-Rheumatic Drugs

Rheumatoid arthritis (RA) is a chronic inflammatory disease that can wreak havoc on the body, including the cardiovascular system. Biologic and targeted synthetic drugs have emerged as powerful weapons against RA, but their impact on vascular health remains a topic of much debate. This systematic review dives into the intricate relationship between these drugs and vascular function, aiming to shed light on their potential effects on cardiovascular risk in patients with RA. The researchers conducted a comprehensive search of available literature to evaluate the vascular effects of these drugs, taking a closer look at their potential benefits and risks for cardiovascular health. The review serves as a valuable guide for understanding the complex interplay between RA treatment and cardiovascular health.

The Vascular Implications of RA Treatment

This systematic review provides a comprehensive overview of the vascular effects of biologic and targeted synthetic drugs used to treat RA. The findings highlight the need for a careful consideration of potential cardiovascular risks associated with these drugs. Clinicians should monitor patients closely for any signs of cardiovascular complications and adjust treatment strategies as needed to optimize both RA control and cardiovascular health.

Navigating the Crossroads of RA and Cardiovascular Health

The intricate relationship between RA and cardiovascular disease presents a unique challenge for clinicians. This systematic review sheds light on the vascular effects of biologic and targeted synthetic drugs used to treat RA, providing valuable insights into their potential impact on cardiovascular risk. The findings emphasize the importance of individualized treatment approaches, considering both the benefits and risks of these medications in relation to each patient's specific needs and cardiovascular health profile.

Dr.Camel's Conclusion

This systematic review serves as a valuable resource for understanding the complex interplay between RA treatment and vascular health. The findings underscore the importance of ongoing research to further explore the cardiovascular effects of biologic and targeted synthetic drugs, ultimately aiming to ensure safe and effective treatment strategies for patients with RA.

Date :
  1. Date Completed 2023-09-13
  2. Date Revised 2023-09-22
Further Info :

Pubmed ID

36991244

DOI: Digital Object Identifier

10.1007/s10067-023-06587-8

SNS
PICO Info
in preparation
Languages

English

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