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Use of a sequential multiple assignment randomized trial to test contingency management and an integrated behavioral economic and mindfulness intervention for buprenorphine-naloxone medication adherence for opioid use disorder.

Author: CowanRonald, DerefinkoKaren J, HandSarah B, HarrisMatt, JohnsonKaren Chandler, MurphyJames G, PeterSamuel C, ThomasFridtjof, WitkiewitzKatie

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

A sequential multiple assignment randomized trial will evaluate the efficacy of two psychological interventions for improving buprenorphine-naloxone adherence in individuals seeking treatment for opioid use disorder (OUD). The study will compare contingency management (CM) and brief motivational interviewing plus substance-free activities session plus mindfulness (BSM) in 280 participants. The primary outcome will be medication adherence, assessed by physician visit attendance and buprenorphine presence in urine. The study will investigate the benefit of sequential treatment decisions following non-adherence.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Buprenorphine-naloxone is a medication shown to improve outcomes for individuals seeking treatment for opioid use disorder (OUD); however, outcomes are limited by low medication adherence rates. This is especially true during the early stages of treatment. METHODS: The present study pro...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061866/

データ提供：米国国立医学図書館（NLM）

A Novel Approach to Boosting Buprenorphine-Naloxone Adherence for Opioid Use Disorder (OUD)

The struggle with opioid use disorder (OUD) is a challenging journey, and medication adherence is often a key factor in successful recovery. This study explores two promising psychological interventions aimed at improving adherence to buprenorphine-naloxone, a medication proven to improve outcomes for individuals seeking treatment for OUD. The study utilizes a sequential multiple assignment randomized trial design, a sophisticated method that allows for flexibility in treatment based on individual responses.

Contingency Management and Integrated Behavioral Economic and Mindfulness Intervention for OUD

The study compares two intervention strategies: contingency management (CM) and brief motivational interviewing plus substance-free activities session plus mindfulness (BSM). The researchers aim to determine which intervention is more effective in promoting adherence to buprenorphine-naloxone, and whether combining these interventions might be beneficial for individuals who initially struggle with adherence.

Improving Adherence for a Healthier Future

This study is like a treasure hunt in the vast desert of OUD treatment. By carefully examining the effectiveness of different interventions, researchers hope to discover the most effective strategies for promoting medication adherence and improving the lives of individuals struggling with OUD. The insights gained from this study could lead to more personalized and effective treatment plans, paving the way for greater success in recovery.

Dr.Camel's Conclusion

This innovative study delves into the complexities of OUD treatment, exploring the effectiveness of different psychological interventions for enhancing medication adherence. By combining rigorous research methods with a flexible approach to treatment, this study promises to shed light on the most effective strategies for promoting recovery. This work is a beacon in the desert of OUD, offering hope for individuals seeking to overcome this challenging condition.

Date :
  1. Date Completed 2023-03-31
  2. Date Revised 2023-04-01
Further Info :

Pubmed ID

36991453

DOI: Digital Object Identifier

PMC10061866

Related Literature

Article Analysis
・Effective treatment of opioid use
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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