The efficacy and safety of buprenorphine for the treatment of depression: A systematic review and meta-analysis.

Author: RibletNatalie B, SchnurrPaula P, ShinerBrian, WattsBradley V, Young-XuYinong

Paper Details 
Original Abstract of the Article :
BACKGROUND: Depressive disorders are common. Many patients with major depression do not achieve remission with available treatments. Buprenorphine has been raised as a potential treatment for depression as well as suicidal behavior but may pose certain risks. METHODS: A meta-analysis comparing the ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/37019069

データ提供:米国国立医学図書館(NLM)

Buprenorphine: A Potential Ally in the Battle Against Depression

Depression is a pervasive and debilitating condition that affects millions worldwide. While numerous treatments are available, many patients fail to achieve remission with conventional therapies. This research explores the potential of buprenorphine, a medication typically used for opioid dependence, as a treatment for depression. They conducted a systematic review and meta-analysis of studies investigating the efficacy, tolerability, and safety of buprenorphine in treating depression. They found that buprenorphine had a small but positive effect on depressive symptoms, particularly when combined with samidorphan. They also found that buprenorphine was generally well-tolerated, with no significant signs of abuse or dependency.

Buprenorphine: A New Direction for Depression Treatment?

This research suggests that buprenorphine might be a valuable addition to the arsenal of treatments for depression. Although its effects are relatively modest, the potential for benefit, combined with its good tolerability, warrants further investigation. These findings offer hope for those seeking alternative treatment options for depression.

Buprenorphine: A Potential Oasis in the Desert of Depression

This research offers a glimmer of hope in the vast desert of depression treatment. While more research is needed to fully understand its potential, buprenorphine could provide a new and effective treatment option for those struggling with this complex condition.

Dr.Camel's Conclusion

This research is a reminder that the search for new treatments for depression is a never-ending journey. Buprenorphine, like a hidden spring in the desert, offers a potential new source of relief, and it's important to continue exploring its role in treating this pervasive condition.

Date :
  1. Date Completed 2023-05-01
  2. Date Revised 2023-06-01
Further Info :

Pubmed ID

37019069

DOI: Digital Object Identifier

NIHMS1890599

Related Literature

SNS
PICO Info
in preparation
Languages

English

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