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Identification of FDA-approved drugs with triple targeting mode of action for the treatment of monkeypox: a high throughput virtual screening study.
Author: DasDorothy, GodaraPriya, MattaparthiVenkata Satish Kumar, NaikBiswajit, PrustyDhaneswar, SrivastavaVarshita
Original Abstract of the Article :
According to the Center for Disease Control and Prevention, as of August 23, 94 countries had confirmed 42,954 Monkeypox Virus cases. As specific monkeypox drugs are not yet developed, the treatment depends on repurposed FDA-approved drugs. According to a recent study, the Monkeypox outbreak is caus...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116100/
データ提供:米国国立医学図書館(NLM)
A Virtual Search for Monkeypox Therapies
Monkeypox, a viral disease that has recently emerged as a global concern, is like a desert storm that can quickly spread and cause chaos. This research delves into the potential of repurposing existing FDA-approved drugs to treat monkeypox, a strategy that could be crucial in the absence of specific monkeypox treatments. It's like searching for shelter in a desert storm, utilizing the resources available to navigate the danger.Utilizing Existing Resources for Monkeypox
The study performs a high-throughput virtual screening to identify FDA-approved drugs that could potentially inhibit multiple viral targets. It's like searching for a multi-purpose tool in the desert, something that can be used for digging, shelter, and defense. The researchers identified 15 triple-targeting drugs, including naldemedine and saquinavir, that could potentially be effective against monkeypox.A Potential Solution for Monkeypox
This research offers a glimmer of hope in the fight against monkeypox. It's like finding a hidden oasis in the midst of a desert storm, offering a chance for respite and recovery. The study's findings provide a starting point for further research and potential development of effective therapies for monkeypox.Dr. Camel's Conclusion
Repurposing existing drugs could be a vital strategy in the fight against monkeypox. This research highlights the potential of virtual screening as a tool for quickly identifying promising candidates for further investigation and development. It's like having a desert guide who can help you navigate the landscape and find the most promising paths for success.Date :
- Date Completed n.d.
- Date Revised 2023-04-26
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