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Clean-DM1, a Korean Polyherbal Formula, Improves High Fat Diet-Induced Diabetic Symptoms in Mice by Regulating IRS/PI3K/AKT and AMPK Expressions in Pancreas and Liver Tissues.
Author: HanXiang, HoTianjun, JungHyo Won, KangSeok Yong, LeeKyung Jae, LiuYi, LyuChenzi, MengXianglong, ParkYong-Ki, WangPiao
Original Abstract of the Article :
OBJECTIVE: To investigate the effects of Clean-DM1 (C-DM1), a polyherbal formulation of Radix Scrophulariae, Radix Astragali, Rhizoma Atractylodis, and Radix Salviae Miltiorrhizae, on high-fat diet (HFD)-induced diabetes mice. METHODS: The information about active components of C-DM1 extract and mo...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/s11655-023-3548-9
データ提供:米国国立医学図書館(NLM)
Unveiling Clean-DM1's Potential for Diabetes Management
This study investigates the potential of Clean-DM1, a Korean polyherbal formulation, in mitigating diabetic symptoms induced by a high-fat diet in mice. The researchers utilized a network pharmacology approach to identify the active components of Clean-DM1 and their potential molecular targets. They then conducted an in vivo study, administering Clean-DM1 to mice with diet-induced diabetes and monitoring various metabolic parameters, including blood glucose levels, body weight, and insulin sensitivity. The study revealed that Clean-DM1 significantly improved diabetic symptoms, suggesting its potential as a natural therapeutic agent for managing diabetes.
Clean-DM1: A Promising Natural Remedy for Diabetes Management
This study provides encouraging evidence for the potential of Clean-DM1, a polyherbal formulation, in managing diabetes. The researchers observed significant improvements in diabetic symptoms, including reduced blood glucose levels, body weight, and insulin resistance, in mice following Clean-DM1 administration. These findings suggest that Clean-DM1 might hold promise as a natural therapeutic agent for managing diabetes and promoting overall metabolic health.
Managing Diabetes: A Holistic Approach
Managing diabetes requires a comprehensive approach that encompasses lifestyle modifications, such as a healthy diet, regular exercise, and stress management, alongside appropriate medical interventions. This study highlights the potential of natural remedies, like Clean-DM1, in complementing traditional therapies. It's crucial to consult with a healthcare professional for personalized advice and to avoid self-treating any health conditions, including diabetes.
Dr.Camel's Conclusion
This study, like a camel navigating a vast desert of complexities, offers a promising new direction for managing diabetes. The researchers have uncovered the potential of Clean-DM1, a polyherbal formulation, to improve diabetic symptoms and promote overall metabolic health. This research encourages further investigation into the long-term effects and potential benefits of Clean-DM1, potentially paving the way for new therapeutic strategies for managing diabetes.
Date :
- Date Completed n.d.
- Date Revised 2023-04-28
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