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Side effects of low-dose tamoxifen: results from a six-armed randomised controlled trial in healthy women.

Author: BergqvistJenny, BorgquistSigne, BäcklundMagnus, CrippaAlessio, CzeneKamila, DiscacciatiAndrea, EklundMartin, ErikssonMikael, GabrielsonMarike, HallPer, HammarströmMattias, LundholmCecilia, TapiaJosé, WengströmYvonne

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Adherence to tamoxifen therapy is suboptimal, and acceptance for primary prevention is poor. Low-dose tamoxifen therapy shows promise. This study describes side effects of standard and low-dose tamoxifen in healthy women using questionnaire data from a randomized controlled trial.
Paper Details　
Original Abstract of the Article :
Adherence to adjuvant tamoxifen therapy is suboptimal, and acceptance of tamoxifen for primary prevention is poor. Published results indicate effect of low-dose tamoxifen therapy. Using questionnaire data from a randomised controlled trial, we describe side effects of standard and low-dose tamoxifen...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307785/

データ提供：米国国立医学図書館（NLM）

Side Effects of Low-Dose Tamoxifen

This study delves into the world of breast cancer prevention and treatment, focusing on the side effects of tamoxifen, a drug that plays a key role in reducing breast cancer risk. Imagine the vast expanse of the desert, dotted with various plants and shrubs, some beneficial, others potentially harmful. Similarly, tamoxifen, while offering protection against breast cancer, can also have side effects. This study, like a careful botanist examining the desert flora, investigates the specific side effects of standard and low-dose tamoxifen in healthy women. The authors, armed with data from a six-armed randomized controlled trial, provide a detailed account of these potential side effects, helping doctors and patients make informed decisions about tamoxifen therapy.

Balancing Benefits and Risks

This study sheds light on the crucial need to weigh the benefits and risks of medication. Just as a traveler in the desert must choose their path carefully, considering both the potential rewards and dangers, patients need to be fully informed about the potential side effects of tamoxifen alongside its proven benefits in reducing breast cancer risk.

Informed Decision-Making

Understanding the potential side effects of tamoxifen is essential for women considering this treatment option. This study provides valuable information for both doctors and patients, helping them make informed decisions about the best course of action. Remember, every individual is different, and what works for one person may not work for another. Open communication between patients and their doctors is key to ensuring the best possible outcomes.

Dr.Camel's Conclusion

Tamoxifen is like a desert oasis, offering protection against breast cancer, but it also has potential side effects. This study helps us navigate the desert of treatment options, making informed decisions about whether this medication is right for you.

Date :
  1. Date Completed 2023-06-30
  2. Date Revised 2023-07-03
Further Info :

Pubmed ID

37149701

DOI: Digital Object Identifier

PMC10307785

Related Literature

Article Analysis
・Side Effects of tamoxifen
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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