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Evaluation of the delirium preventive effect of dual orexin receptor antagonist (DORA) in critically ill adult patients requiring ventilation with tracheal intubation at an advanced emergency center: A single-center, retrospective, observational study.
Author: KoamiHiroyuki, MatsuokaAyaka, MizoguchiYoshito, MonjiAkira, Murakawa-HirachiToru, SakamotoYuichiro, ShimanoeChisato, ShinadaKota, SogawaRintaro
Original Abstract of the Article :
ICU delirium reportedly contributes to increased mortality attributed to underlying diseases, long-term cognitive decline, and increased healthcare costs. Dual orexin receptor antagonists (DORAs), suvorexant and lemborexant, have been suggested for preventing ICU delirium. Although ventilator manage...See full text at original site
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引用元:
https://doi.org/10.1016/j.genhosppsych.2023.03.010
データ提供:米国国立医学図書館(NLM)
Preventing Delirium in Critically Ill Patients: A New Hope?
Delirium, a state of altered consciousness, is a common and serious complication in critically ill patients. It's like a disorienting sandstorm that can disrupt a patient's recovery. This study explores the potential of dual orexin receptor antagonists (DORAs), a type of medication that targets specific brain receptors, in preventing delirium in critically ill patients requiring mechanical ventilation. The researchers analyzed data from a single-center, retrospective, observational study, examining the impact of DORAs on delirium rates. While the results suggest that DORAs may have a potential benefit in preventing delirium, further research is needed to confirm their efficacy. This is like discovering a potential source of water in the desert, but more exploration is needed to confirm its reliability and accessibility.
DORAs: A Potential Weapon in the Fight Against Delirium
This research offers a glimpse of hope for preventing delirium in critically ill patients. DORAs may hold promise as a potential treatment option, offering a way to reduce the incidence and severity of this debilitating condition. This is like finding a hidden spring in the desert, providing a much-needed source of relief from the harsh conditions.
Delirium: A Complex Condition Requiring Comprehensive Care
Delirium is a complex condition that requires comprehensive care. This study underscores the importance of ongoing research and development of new treatments to address this challenging issue. This is like a continuous journey of exploration in the desert, searching for new resources and solutions to improve the well-being of those in need.
Dr.Camel's Conclusion
This research is like a promising oasis in the desert of critical care. DORAs may offer a potential solution for preventing delirium, but more research is needed to solidify their role in managing this complex condition. We must continue to explore new pathways to improve the well-being of those navigating the challenges of critical illness.
Date :
- Date Completed 2023-06-13
- Date Revised 2023-06-15
Further Info :
Related Literature
English
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