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Bench-to-bedside: Innovation of small molecule anti-SARS-CoV-2 drugs in China.

Author: WangZhonglei, YangLiyan

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This review discusses the development of small molecule anti-SARS-CoV-2 drugs in China.
Paper Details　
Original Abstract of the Article :
The ongoing COVID-19 pandemic has resulted in millions of deaths globally, highlighting the need to develop potent prophylactic and therapeutic strategies against SARS-CoV-2. Small molecule inhibitors (remdesivir, Paxlovid, and molnupiravir) are essential complements to vaccines and play important r...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193775/

データ提供：米国国立医学図書館（NLM）

Small Molecule Drugs: A Promising Weapon Against SARS-CoV-2

The COVID-19 pandemic has shaken the world, prompting an urgent search for effective treatments. This research focuses on the development of small molecule inhibitors, a type of drug that can effectively combat the virus responsible for COVID-19, SARS-CoV-2.

The Role of Small Molecule Inhibitors

The study highlights the progress made in China in developing small molecule inhibitors, such as azvudine, VV116, FB2001, WPV01, pentarlandir, and cepharanthine. These drugs have shown promising results in clinical trials, offering potential therapeutic options for COVID-19 patients.

The Role of Small Molecule Inhibitors

This study underscores the remarkable progress made in drug development for COVID-19. It provides hope for the future, as researchers continue to refine and develop new treatments to combat this global health crisis.

Dr.Camel's Conclusion

This study is like a caravan of scientists traversing the vast desert of COVID-19 research. They are relentlessly searching for effective treatments, and these small molecule inhibitors represent a promising new weapon in the fight against this deadly virus.
Date :
  1. Date Completed 2023-07-25
  2. Date Revised 2023-11-06
Further Info :

Pubmed ID

37229831

DOI: Digital Object Identifier

PMC10193775

Related Literature

Article Analysis
・Side Effects of molnupiravir
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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