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Measles, mumps, and rubella vaccine at age 6 months and hospitalisation for infection before age 12 months: randomised controlled trial.

Author: HerlufsenEmma Hoppe, JensenAndreas, MalonMichelle, StensballeLone Graff, SvenssonJannet, SørensenJesper Kiehn, VittrupDorthe Maria, ZimakoffAnne Cathrine

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This randomized, double-blinded, placebo-controlled trial tested for potential non-specific effects of an additional, early measles, mumps, and rubella (MMR) vaccine on the risk of infection-related hospitalization in infants. Findings did not support the hypothesis that early MMR vaccination decreases the rate of hospitalizations for non-targeted infection.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To test for potential non-specific effects of an additional, early measles, mumps, and rubella (MMR) vaccine at age 5-7 months on risk of infection related hospitalisation before age 12 months. DESIGN: Randomised, double blinded, placebo controlled trial. SETTING: Denmark, a high income...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245144/

データ提供：米国国立医学図書館（NLM）

Early MMR Vaccination and Hospitalization for Infections in Infants

This study investigates the potential impact of early MMR vaccination on the risk of hospitalization for infections in infants. It's like navigating a desert landscape, trying to understand the complex interplay of factors that influence a child's health. Researchers used a randomized, double-blinded, placebo-controlled trial, a gold standard method for evaluating the effectiveness of interventions. They studied 6,540 infants in Denmark, a country with a low exposure to MMR.

Early MMR Vaccination Doesn't Seem to Increase the Risk of Hospitalization for Infections

The study found no evidence that early MMR vaccination increased the risk of hospitalization for infections. This finding is like finding a safe and well-trodden path through a potentially dangerous desert landscape. It provides reassuring evidence for parents seeking to protect their children from vaccine-preventable diseases.

Early MMR Vaccination Might Offer Additional Benefits

While the study did not find a significant impact on the risk of hospitalization for infections, it did suggest a possible increase in the duration of hospital stays and antibiotic prescriptions among those who received the early MMR vaccine. It's like discovering a hidden spring in the desert – an unexpected bonus that may require further exploration.

Dr.Camel's Conclusion

This research is like a desert guide, providing valuable information for parents and healthcare professionals navigating the complex landscape of infant health. The findings offer reassurance that early MMR vaccination, a crucial tool in protecting children from preventable diseases, does not appear to increase the risk of hospitalization for infections. While further research is needed to understand the potential nuances of the findings, the study provides valuable insight into the safety and efficacy of this important vaccination.

Date :
  1. Date Completed 2023-06-09
  2. Date Revised 2023-06-12
Further Info :

Pubmed ID

37286215

DOI: Digital Object Identifier

PMC10245144

Related Literature

Article Analysis
・Effects of mmr vaccine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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