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Effects of Antihypertensive Treatment on Left and Right Ventricular Global Longitudinal Strain and Diastolic Parameters in Patients with Hypertension and Obstructive Sleep Apnea: Randomized Clinical Trial of Chlorthalidone plus Amiloride vs. Amlodipine.

Author: CicheleroFábio T, FoppaMurilo, FuchsFlávio D, FuchsSandra C, JorgeJuliano A, LuccaMarcelo B, MartinezDenis, SantosAngela B S, de OliveiraGeórgia P F

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Hypertension is common in patients with obstructive sleep apnea (OSA). This study compared the effects of diuretics and amlodipine on echocardiographic parameters in patients with moderate OSA and hypertension. The findings suggest that both treatments have small, similar effects on these parameters, indicating that they do not significantly impact the relationship between OSA and hypertension.
Paper Details　
Original Abstract of the Article :
Hypertension is highly prevalent in patients with obstructive sleep apnea (OSA), and fluid retention with its nighttime rostral distribution is one potential mechanism. We tested whether or not diuretics differ from amlodipine in their impact on echocardiographic parameters. Patients with moderate O...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253604/

データ提供：米国国立医学図書館（NLM）

The Link Between Hypertension and Sleep Apnea: A Desert of Intertwined Conditions

Hypertension and obstructive sleep apnea (OSA) are like two deserts, each with their own challenges, but sometimes found intertwined in the same landscape. This research investigates the impact of different antihypertensive treatments on the heart in patients with both hypertension and OSA. The authors compared the effects of diuretics (chlorthalidone plus amiloride) to amlodipine, a calcium channel blocker.

Navigating the Shifting Sands of Heart Health

The study found that both diuretics and amlodipine effectively lowered blood pressure and had minimal effects on heart function. This is like discovering two different paths through the desert, both leading to similar outcomes. The results suggest that both medications can be effective in managing hypertension in patients with OSA without significantly impacting heart health.

Finding Balance in the Desert of Cardiovascular Health

This research underscores the importance of understanding the complex interplay between hypertension and OSA. It's like learning to navigate the shifting sands of these two deserts, understanding their potential impact on heart health and finding the right treatments to maintain balance. Consulting with a doctor is crucial for creating a personalized treatment plan that addresses both conditions.

Dr. Camel's Conclusion

The research on antihypertensive treatment in patients with hypertension and OSA provides valuable insights into the intertwined world of these two conditions. It's like exploring a desert landscape, understanding the potential impact of each condition on the heart and finding the right tools to navigate the terrain. By understanding the nuances of these conditions and working with a healthcare professional, we can find the path to better cardiovascular health.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-06-12
Further Info :

Pubmed ID

37297980

DOI: Digital Object Identifier

PMC10253604

Related Literature

Article Analysis
・Effects of amiloride・Effects of chlorthalidone
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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