Paper Details

  1. Home
  2. Paper Details

Fecal microbiota transplantation for the treatment of irritable bowel syndrome: A systematic review and meta-analysis.

Author: AroniadisOlga C, BrummerRobert Jan, ColdFrederik, GluudLise Lotte, HalkjærSofie Ingdam, HolsterSavanne, HolvoetTom, Højer ChristensenAlice, KönigJulia, LahtinenPerttu, LoBobby, PetersenAndreas Munk

Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Irritable bowel syndrome (IBS) is a common digestive disorder that affects people's lives, work, and healthcare costs. Research shows that people with IBS have different bacteria in their gut (gut dysbiosis). Transferring healthy gut bacteria from one person to another (fecal microbiota transplantation or FMT) is being explored as a potential treatment for IBS.
Paper Details　
Original Abstract of the Article :
Irritable bowel syndrome (IBS) is the most prevalent gastrointestinal disorder in developed countries and reduces patients' quality of life, hinders their ability to work, and increases health care costs. A growing number of trials have demonstrated an aberrant gut microbiota composition in IBS, als...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280798/

データ提供：米国国立医学図書館（NLM）

Fecal Microbiota Transplantation: A New Frontier for IBS Treatment?

Greetings, fellow adventurers, Dr. Camel here, ready to embark on a journey into the fascinating world of the gut microbiome. This systematic review and meta-analysis explores the potential of fecal microbiota transplantation (FMT) as a treatment for irritable bowel syndrome (IBS), a common digestive disorder that can make life feel like a desert of discomfort.

The study delves into the intricate relationship between the gut microbiome and IBS, highlighting the potential for restoring a healthy balance of bacteria in the gut, much like replenishing an oasis with fresh water. Researchers have found that FMT, a procedure that involves transferring fecal matter from a healthy donor to a recipient, can potentially improve symptoms of IBS.

A New Hope for IBS Patients

This study suggests that FMT could offer a promising treatment option for IBS, a condition that often defies conventional therapies. Imagine finding a hidden oasis in the vast desert of IBS, offering relief from the debilitating symptoms. FMT could potentially be a game-changer for individuals struggling with this condition, providing a path toward better gut health and a higher quality of life.

The Power of the Gut Microbiome

This study underscores the importance of the gut microbiome in maintaining overall health. It's a reminder that our gut is a vast and complex ecosystem that plays a critical role in our well-being. By understanding the intricate balance of bacteria in our gut, researchers can develop new and effective therapies for a variety of conditions, including IBS.

Dr. Camel's Conclusion

This systematic review and meta-analysis provides compelling evidence that FMT could be a viable treatment option for IBS. It's a testament to the remarkable power of our gut microbiome and the potential for restoring its balance to improve health and well-being. As a researcher, I'm excited to see the continued exploration of FMT and other microbiome-based therapies as we strive to find new and innovative ways to navigate the deserts of disease and promote better health for all.

Date :
  1. Date Completed 2023-06-26
  2. Date Revised 2023-07-01
Further Info :

Pubmed ID

37346153

DOI: Digital Object Identifier

PMC10280798

Related Literature

Article Analysis
・Effective treatment of irritable bowel syndrome
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.