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Movement disorders associated with antiseizure medications: A real-world disproportionality analysis of the Food and Drug Administration Adverse Event Reporting System.
Author: ChenShengyang, HuangWei, LiuMaobai, WeiZipeng, WuXuemei, XieHelin, ZhouJianxing
Original Abstract of the Article :
Patients with epilepsy often require long-term use of antiseizure medications (ASMs) to control their seizures. However, movement disorders (MDs) related to ASMs can significantly impact their quality of life. This study aims to analyse MDs related to ASMs in the Food and Drug Administration Adverse...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/bcp.15836
データ提供:米国国立医学図書館(NLM)
Movement Disorders Associated with Antiseizure Medications: A Real-World Analysis
Epilepsy management often involves long-term use of antiseizure medications (ASMs), but these drugs can sometimes cause movement disorders (MDs) that significantly impact patients' lives. This study examines the prevalence of MDs associated with ASMs in the Food and Drug Administration Adverse Event Reporting System database, aiming to improve the safe use of these medications. The authors analyzed a large real-world dataset to identify trends and patterns in ASM-related MDs, providing valuable information for healthcare professionals.
The Importance of Understanding Adverse Effects
The study highlights the importance of recognizing and managing potential adverse effects associated with ASMs. By analyzing real-world data, researchers can gain a better understanding of the frequency and severity of MDs, allowing for more informed decision-making regarding medication selection and management.
Balancing Benefits and Risks
The study underscores the delicate balance between the benefits and risks of ASM therapy. This research provides important information for healthcare professionals and patients to make informed decisions about ASM treatment, ensuring that the benefits of seizure control are balanced with the potential for adverse effects.
Dr. Camel's Conclusion
Think of ASM therapy as a journey across a vast desert. While it offers the potential for controlling seizures, there are hidden risks and unexpected challenges along the way. This research provides a roadmap for navigating this complex terrain, helping to identify and manage potential movement disorders, ensuring a smoother and safer journey for patients.
Date :
- Date Completed 2023-10-23
- Date Revised 2023-10-25
Further Info :
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English
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