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Global treatment outcomes of extensively drug-resistant tuberculosis in adults: A systematic review and meta-analysis.

Author: AndersenAase Bengaard, DahlVictor Naestholt, HolmgaardFreja Breth, LangeChristoph, LillebaekTroels, MikkelsenMads Kristian Duborg, PedersenOle Skouvig, SotgiuGiovanni, WejseChristian Morberg

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study estimates the proportion of patients with extensively drug-resistant tuberculosis (XDR-TB) globally who achieved successful treatment outcomes. XDR-TB is a serious and difficult-to-treat form of tuberculosis.
Paper Details　
Original Abstract of the Article :
Historically, extensively drug-resistant tuberculosis has been notoriously difficult to treat with devasting outcomes. As we are coming to the end of an era where the 2006 extensively drug-resistant tuberculosis definitions and old treatment regimens are being replaced, we aimed to estimate the prop...See full text at original site
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引用元：
https://doi.org/10.1016/j.jinf.2023.06.014

データ提供：米国国立医学図書館（NLM）

Extensively Drug-Resistant Tuberculosis (XDR-TB): A Global Challenge

Tuberculosis (TB), a respiratory infection, can be like a stubborn desert weed that's hard to eradicate. In some cases, the bacteria responsible for TB become resistant to multiple drugs, leading to a condition called extensively drug-resistant TB (XDR-TB). This study examined the global treatment outcomes of XDR-TB, analyzing data from various studies to understand the challenges and successes in treating this complex condition. The study aimed to estimate the proportion of XDR-TB patients who achieve successful treatment outcomes and identify key factors influencing treatment success.

Global Treatment Outcomes of XDR-TB

The study found that while significant progress has been made in treating XDR-TB, it remains a serious challenge. The proportion of patients achieving successful treatment outcomes varies significantly across different regions. The study highlights the need for ongoing efforts to improve treatment regimens, access to care, and patient adherence to treatment.

The Importance of Collaborative Efforts

This study underscores the need for a multi-pronged approach to combat XDR-TB. Global collaboration, improved diagnostic tools, and effective treatment regimens are crucial to improve outcomes. Just as a caravan relies on the strength of its members to navigate a perilous desert journey, tackling XDR-TB requires a collective effort.

Dr.Camel's Conclusion

The fight against XDR-TB is a global endeavor. This study underscores the importance of collaborative efforts to develop more effective treatment strategies, improve access to care, and ensure patient adherence. By working together, we can hope to overcome this challenge and create a healthier world for all.

Date :
  1. Date Completed 2023-08-09
  2. Date Revised 2023-08-09
Further Info :

Pubmed ID

37356629

DOI: Digital Object Identifier

10.1016/j.jinf.2023.06.014

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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