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Quantitative Fundus Autofluorescence in Systemic Chloroquine/Hydroxychloroquine Therapy: One Year Follow-Up.

Author: AchThomas, BerlinAndreas, HillenkampJost, HolzFrank G, KleefeldtNikolai, RadunVictoria, ReichelClara, SaßmannshausenMarlene, SloanKenneth R, TarauIoana-Sandra

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Patients taking chloroquine/hydroxychloroquine (CQ/HCQ) showed a significant increase in quantitative autofluorescence (QAF) levels from baseline to follow-up examination. This finding may be a useful tool for monitoring CQ/HCQ treatment.
Paper Details　
Original Abstract of the Article :
PURPOSE: Systemic chloroquine/hydroxychloroquine (CQ/HCQ) can cause severe ocular side effects including bull's eye maculopathy (BEM). Recently, we reported higher quantitative autofluorescence (QAF) levels in patients with CQ/HCQ intake. Here, QAF in patients taking CQ/HCQ in a 1-year follow-up is ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337803/

データ提供：米国国立医学図書館（NLM）

Monitoring Chloroquine/Hydroxychloroquine Therapy: A New Tool for Eye Health

Chloroquine and hydroxychloroquine are medications used to treat various conditions, but they can also have serious side effects on the eyes. This research explores the potential of quantitative fundus autofluorescence (QAF) imaging as a tool for monitoring patients taking these medications. It's like having a special telescope to peer into the depths of the desert and assess the health of a precious oasis. The study investigates QAF levels in patients taking chloroquine/hydroxychloroquine and compares them to healthy individuals.

A New Lens: Using QAF Imaging to Monitor Eye Health

This study suggests that QAF imaging could be a valuable tool for monitoring patients taking chloroquine/hydroxychloroquine. This is like using a sophisticated map to track changes within a desert landscape, allowing for early detection of potential issues. The researchers found that QAF levels were significantly increased in patients taking these medications, highlighting the potential of QAF as a screening tool for detecting early signs of ocular toxicity.

Protecting Eye Health: Early Detection and Intervention

This research emphasizes the importance of early detection and intervention in managing potential ocular toxicity associated with chloroquine/hydroxychloroquine treatment. The study suggests that QAF imaging could be a valuable addition to the standard screening tools used in monitoring patients. It's like having a vigilant scout to identify potential threats within the desert landscape of eye health, allowing for timely intervention and protection.

Dr. Camel's Conclusion

This research offers a promising new approach to monitoring eye health in patients taking chloroquine/hydroxychloroquine. The study highlights the potential of QAF imaging as a valuable tool for early detection and intervention.

Date :
  1. Date Completed 2023-07-10
  2. Date Revised 2023-11-16
Further Info :

Pubmed ID

37418250

DOI: Digital Object Identifier

PMC10337803

SNS
PICO Info
in preparation
Languages

English

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