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Immune checkpoint inhibitor refractory colitis leading to total colectomy in a melanoma patient.

Author: BaczewskaN, BaurainJ-F, CocheJ-C, DuckL, LaterreE, PhilippartM, SipletJ, StainierL

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.

Overview

This report describes a case of severe refractory colitis in a patient treated with Nivolumab, an anti-PD-1 immunotherapy, for advanced melanoma. While immunotherapy is effective for melanoma, managing its side effects is crucial. This case highlights the importance of early recognition and aggressive management of immunotherapy-related colitis, as some cases may require surgical intervention.
Paper Details　
Original Abstract of the Article :
Immunotherapy is becoming more and more relevant in the treatment of advanced melanoma. Proper management of its side effects can prevent severe complications. We describe the case of a 73-year-old patient with severe refractory colitis secondary to immunotherapy. The patient has been treated for 6 ...See full text at original site
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引用元：
https://doi.org/10.51821/86.2.10400

データ提供：米国国立医学図書館（NLM）

Immunotherapy: A Powerful Weapon with Unexpected Side Effects

This case study sheds light on the potential for immunotherapy, a promising new approach to cancer treatment, to cause severe and unexpected side effects. It's like discovering a hidden oasis that, while offering refuge, can also harbor unexpected dangers. The researchers describe a case where a melanoma patient developed severe colitis, a debilitating inflammation of the colon, as a result of immunotherapy treatment.

Navigating the Side Effects of Immunotherapy

The case study underscores the importance of being aware of the potential for serious side effects associated with immunotherapy. It's like navigating a desert landscape where the unexpected can arise at any moment. Close monitoring and careful management are crucial in ensuring that the benefits of immunotherapy outweigh the risks.

A Reminder of the Complexities of Cancer Treatment

This case study serves as a reminder that cancer treatment is a complex and evolving field. It's like a vast desert landscape with constantly shifting sands, requiring ongoing research and careful consideration of the latest advancements. The case also highlights the need for continued research into the mechanisms of immunotherapy side effects, allowing for better management and prevention of these complications.

Dr.Camel's Conclusion

Immunotherapy is a powerful tool in the fight against cancer, but it's not without its risks. As with any new frontier, we must proceed with caution and vigilance, carefully monitoring patients for any potential side effects. By understanding the complexities of immunotherapy, we can better navigate its potential benefits and challenges, ensuring the best possible outcomes for cancer patients.

Date :
  1. Date Completed 2023-07-12
  2. Date Revised 2023-07-18
Further Info :

Pubmed ID

37428174

DOI: Digital Object Identifier

10.51821/86.2.10400

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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