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A randomized trial comparing the 52-mg levonorgestrel system with combination oral contraceptives for treatment of heavy menstrual bleeding.

Author: ClarkMelissa A, MattesonKristen A, RakerChristina A, ValcinJosie

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Overview

This randomized trial compared the effectiveness of the 52-mg levonorgestrel intrauterine system (LNG-IUS) with combined oral contraceptives (COCs) for improving quality of life in individuals with self-reported heavy menstrual bleeding. Both LNG-IUS and COCs significantly improved bleeding-related quality of life, with no significant difference between the two groups at 6 or 12 months. The study concludes that both LNG-IUS and COCs are effective options for improving bleeding-related quality of life, and patients should be counseled accordingly.
Paper Details　
Original Abstract of the Article :
BACKGROUND: The levonorgestrel intrauterine system and combined oral contraceptives are the 2 most commonly used nonsurgical treatments for heavy menstrual bleeding in the United States. However, there are limited data on their relative effectiveness and on their impact on bleeding-specific quality ...See full text at original site
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引用元：
https://doi.org/10.1016/j.ajog.2023.07.049

データ提供：米国国立医学図書館（NLM）

Heavy Menstrual Bleeding: A Journey Through Treatment Options

Heavy menstrual bleeding can significantly impact a woman's quality of life. This study compares the effectiveness of two common treatments: the levonorgestrel intrauterine system and combined oral contraceptives. The researchers, like explorers seeking the best route through a challenging terrain, conducted a randomized trial involving women who self-reported heavy menstrual bleeding. They aimed to determine which treatment option led to greater improvements in bleeding-related quality of life.

Treatment Effectiveness: Finding the Right Path in the Desert of Menstrual Bleeding

The study's findings are like a compass guiding us towards effective treatment options. Both the levonorgestrel intrauterine system and combined oral contraceptives were effective in improving bleeding-related quality of life. However, there was no significant difference between the two treatment groups in terms of improvement in Menstrual Bleeding Questionnaire scores at 6 or 12 months.

Navigating the Desert of Menstrual Bleeding: Personalized Treatment

This study highlights the importance of personalized treatment approaches for heavy menstrual bleeding. While both the levonorgestrel intrauterine system and combined oral contraceptives are effective options, the best choice for each individual may vary based on personal preferences, medical history, and lifestyle factors. It's like choosing the path that best suits your needs in a vast desert.

Dr.Camel's Conclusion

This study provides valuable insights for women experiencing heavy menstrual bleeding. It underscores the importance of personalized treatment approaches, considering both treatment efficacy and individual preferences. It's a reminder that the journey through health challenges can be navigated with greater ease and effectiveness when we have the right tools and support.

Date :
  1. Date Completed 2023-12-06
  2. Date Revised 2023-12-13
Further Info :

Pubmed ID

37536486

DOI: Digital Object Identifier

10.1016/j.ajog.2023.07.049

Related Literature

Article Analysis
・Effects of levonorgestrel intrauterine system
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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