Lemborexant levels in breast milk after single doses in healthy, lactating women.

Author: AluriJagadeesh, BrimhallDarin, ChengJocelyn Y, HallNancy, MolineMargaret, RawalSumit

Paper Details 
Original Abstract of the Article :
AIMS: The aim of this study is to determine the cumulative amount of lemborexant (a competitive dual orexin receptor antagonist approved to treat adults with insomnia) excreted in human breast milk and the relative infant dose (RID) as a proportion of daily maternal dose. METHODS: E2006-A001-010 wa...See full text at original site
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引用元:
https://doi.org/10.1111/bcp.15880

データ提供:米国国立医学図書館(NLM)

Lemborexant in Breast Milk: Navigating the Desert of Motherhood

Dr. Camel here, ready to address a topic that concerns many mothers: the safety of medications during breastfeeding. This study investigated the presence of lemborexant, a medication used to treat insomnia, in breast milk. The researchers wanted to determine the amount of lemborexant transferred to the infant through breast milk and assess its potential impact on the infant's health.

Lemborexant in Breast Milk: A Desert Oasis of Safety

The study found that trace amounts of lemborexant were detected in breast milk, but the levels were significantly low. Furthermore, the study reported that lemborexant was well tolerated by the lactating mothers. This is great news, like discovering a small, hidden spring in a vast desert! It suggests that lemborexant use by breastfeeding mothers is likely safe for their infants.

Lemborexant and Breastfeeding: Finding a Balance

While this study provides encouraging results, it's important to consult with a healthcare professional before taking any medication while breastfeeding. Remember, every mother's journey through the desert of motherhood is unique, and individual needs may vary. It's all about finding the right balance between the benefits and risks of medications, ensuring both the mother's well-being and the infant's safety.

Dr. Camel's Conclusion

This study offers a glimmer of hope for breastfeeding mothers seeking treatment for insomnia. It suggests that lemborexant can be used with relative safety while breastfeeding. However, it's essential to consult with a healthcare professional to make informed decisions about medication use during breastfeeding. Remember, the desert of motherhood is vast and often unpredictable, but with the right guidance and support, we can find our way to a safe and healthy oasis!

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-08-24
Further Info :

Pubmed ID

37565541

DOI: Digital Object Identifier

10.1111/bcp.15880

Related Literature

SNS
PICO Info
in preparation
Languages

English

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