Paper Details
- Home
- Paper Details
Coadministered pneumococcal conjugate vaccine decreases immune response to hepatitis A vaccine: a randomized controlled trial.
Author: HerzogChristian, HutseVeronik, KanteleAnu, KäyhtyHelena, OllgrenJukka, PakkanenSari H, RiekkinenMarianna, RomboLars, RoukaertsInge
Original Abstract of the Article :
OBJECTIVES: We explored the influence of coadministration on safety and immunogenicity of the most common travellers' vaccine hepatitis A (HepA) and the pneumococcal conjugate vaccine (PCV) increasingly used both at home and before travel. METHODS: Volunteers aged ≥18 years (n = 305) were randomly ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.cmi.2023.08.006
データ提供:米国国立医学図書館(NLM)
Co-administration of Vaccines: A Balancing Act
The world of travel vaccinations is vast and complex, with many different vaccines being recommended for different destinations. In this study, the researchers investigated the effects of co-administering two common travel vaccines: the pneumococcal conjugate vaccine (PCV13) and the hepatitis A vaccine (HepA). The study, conducted with a randomized controlled trial, aimed to explore the potential impact of co-administration on the safety and immunogenicity of both vaccines.
The study found that while co-administering PCV13 and HepA didn’t cause safety concerns, it did significantly impair the immune response to the HepA vaccine. The researchers observed that those who received both vaccines simultaneously had lower levels of protective antibodies against hepatitis A compared to those who received only the HepA vaccine. This finding suggests that co-administering these two vaccines may not be the best approach, particularly when considering the importance of robust protection against hepatitis A, especially for travelers visiting regions with high transmission rates.
Co-administration: A Potential Issue for Travelers
This study offers valuable insights into the potential impact of co-administering vaccines, highlighting the need for further research and consideration for optimizing vaccine schedules. The results suggest that the current practice of co-administering PCV13 and HepA may not be the most effective strategy and might necessitate a reevaluation of vaccination strategies for travelers.
Think Before You Travel!
As a discerning traveler, understanding the potential interactions between different vaccines is paramount. The results of this study suggest that co-administering PCV13 and HepA may not be the optimal approach, particularly for individuals seeking robust protection against hepatitis A. It’s important to consult with your healthcare provider regarding the best vaccination schedule for your specific travel plans and health conditions.
Dr. Camel's Conclusion
Just like a camel carefully navigates the treacherous sands of the desert, it’s essential to approach vaccine co-administration with caution. The researchers have revealed a potentially significant interaction between PCV13 and HepA, prompting a need for further exploration and optimization of vaccination strategies. Remember, a well-informed traveler is a safe traveler!
Date :
- Date Completed 2023-11-29
- Date Revised 2023-11-29
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.