Inpatient Low-dose Transitions From Full Agonist Opioids Including Methadone Onto Long-acting Depot Buprenorphine: Case Series From a Multicenter Clinical Trial.

Author: BradyKathleen T, FrankCynthia A, LevinFrances R, LitwinAlain H, NunesEdward V, NunezJohnathan, RothPrerana, SchadeMeredith, SevalNikhil, SpringerSandra A, StrongMichelle

Paper Details 
Original Abstract of the Article :
Persons with opioid use disorder (OUD) suffer disproportionately from morbidity and mortality related to serious addiction-related infections requiring hospitalization. Long-acting buprenorphine (LAB) is an underused medication for OUD that may facilitate linkage to care and treatment retention when...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/37579095

データ提供:米国国立医学図書館(NLM)

Inpatient Low-dose Transitions From Full Agonist Opioids Including Methadone Onto Long-acting Depot Buprenorphine: Case Series From a Multicenter Clinical Trial

This study addresses the challenge of transitioning patients with opioid use disorder (OUD) from full agonist opioids, like a harsh desert landscape, to long-acting buprenorphine, a more sustainable pathway to recovery. The research explores the use of long-acting buprenorphine (LAB) as a potential solution to improve treatment retention and reduce morbidity and mortality associated with OUD.

Bridging the Gap in Opioid Treatment

The study highlights the potential benefits of transitioning patients to LAB in the inpatient setting, like navigating a perilous desert journey. The researchers found that LAB can facilitate linkage to care and treatment retention, potentially leading to improved outcomes. However, they also acknowledge the complexities of transitioning patients from full agonists to partial agonists, emphasizing the need for careful management.

A Path Towards Recovery

This research offers hope for patients with OUD, like a well-spring in the desert. The study suggests that LAB can be a valuable tool for improving treatment retention and reducing the risk of relapse. By providing a more stable and sustainable treatment option, we can help patients navigate their journey towards recovery and build a brighter future.

Dr.Camel's Conclusion

This research, like a caravan traversing a challenging desert, highlights the importance of finding innovative ways to treat opioid use disorder. The study suggests that long-acting buprenorphine holds promise for improving treatment retention and reducing the burden of this complex disease. This research is a beacon of hope, guiding us towards a future where patients with OUD can access the care they need to achieve lasting recovery.
Date :
  1. Date Completed 2023-11-06
  2. Date Revised 2023-11-13
Further Info :

Pubmed ID

37579095

DOI: Digital Object Identifier

NIHMS1856657

Related Literature

SNS
PICO Info
in preparation
Languages

English

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